New injection shows promise for Hard-to-Treat lung condition
NCT ID NCT07593027
First seen Jun 27, 2026 · Last updated Jul 23, 2026 · Updated 2 times
Summary
This study tests an investigational drug called IMC-003 in 120 adults with pulmonary arterial hypertension (PAH), a serious lung condition that makes the heart work harder. Participants receive multiple injections of the drug or a placebo, alongside their usual treatments. The goal is to check if the drug is safe and to see if it improves blood flow in the lungs over 24 weeks.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Fujian Medical University Union Hospita
NOT_YET_RECRUITINGFuzhou, Fujian, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Fuwai Center China Cardiovascular Hospital
NOT_YET_RECRUITINGZhengzhou, Henan, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Gansu Provincial Hospital
RECRUITINGLanzhou, Gansu, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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General Hospital of the Northern Theater Command
NOT_YET_RECRUITINGShenyang, Liaoning, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Guangdong Provincial People's Hospital
RECRUITINGGuangzhou, Guangdong, China
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Guangdong Provincial People's Hospital
RECRUITINGGuangzhou, Guangdong, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Kunming Yan'an Hospital
NOT_YET_RECRUITINGKunming, Yunnan, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Qilu Hospital of Shandong University
RECRUITINGJinan, Shangdong, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Shanghai Chest Hospital
NOT_YET_RECRUITINGShanghai, Shanghai Municipality, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Shanghai Pulmonary Hospital
NOT_YET_RECRUITINGShanghai, Shanghai Municipality, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Shanghai Tongji Hospital
RECRUITINGShanghai, Shanghai Municipality, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Sichuan Provincial People's Hospital
NOT_YET_RECRUITINGChengdu, Sichuan, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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The Affiliated Hospital of Guizhou Medical University
NOT_YET_RECRUITINGGuiyang, Guizhou, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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The First Affiliated Hospital of Nanchang University
NOT_YET_RECRUITINGNanchang, Jiangxi, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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The First Affiliated Hospital of Zhejiang University School of Medicine
NOT_YET_RECRUITINGHangzhou, Zhejiang, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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The First Affiliated Hospital of Zhengzhou University
RECRUITINGZhengzhou, Henan, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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The Second Affiliated Hospital Zhejiang University School of Medicine
RECRUITINGHangzhou, Zhejiang, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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The Second Hospital of Tianjin Medical University
NOT_YET_RECRUITINGTianjin, Tianjin Municipality, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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The Second Xiangya Hospital of Central South University
NOT_YET_RECRUITINGChangsha, Hunan, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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The first hospital of Jilin University
RECRUITINGJilin City, Changchun, China
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The first hospital of Jilin University
RECRUITINGJilin City, Changchun, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Tianjin Medical University General Hospital
RECRUITINGTianjin, Tianjin Municipality, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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West China Hospital, Sichuan University
NOT_YET_RECRUITINGChengdu, Sichuan, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Wuhan Asia Heart Hospital
RECRUITINGWuhan, Hubei, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Xiamen Hospital of T.C.M.
RECRUITINGXiamen, Fujian, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Xuanwu Hospital Capital Medical University
NOT_YET_RECRUITINGBeijing, Beijing Municipality, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Xuzhou Central Hospital
RECRUITINGXuzhou, Jiangsu, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Zhongnan Hospital of Wuhan University
NOT_YET_RECRUITINGWuhan, Hubei, China
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Zhongnan Hospital of Wuhan University
NOT_YET_RECRUITINGWuhan, Hubei, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Which PAH treatment strategy works better: adding a third drug or increasing the dose?
- Lung patients may soon do rehab from home via app
- Which drug is best for pulmonary hypertensive crisis? new trial aims to find out
- New PAH drug IKT-001 moves to Long-Term safety check
- New hope for PAH patients: Extended-Release tacrolimus enters phase 3 trial
- Could a daily shot help control rare lung disease?