New pill hopes to ease breathing in rare lung conditions

NCT ID NCT07175038

First seen Jun 27, 2026 · Last updated Aug 11, 2026 · Updated 2 times

Summary

This study tests an experimental oral drug called ROC-101 in 40 adults with pulmonary arterial hypertension (PAH) or pulmonary hypertension linked to interstitial lung disease (ILD-PH). Participants take the drug alongside their standard care for 24 weeks, with a long-term follow-up. The main goal is to see if the drug safely improves blood flow in the lungs and reduces symptoms like shortness of breath.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Aou Policlinico Umberto I - Uoc Malattie Cardiovascolari (Padiglione Viii)

    RECRUITING

    Rome, Rome, 00161, Italy

    Contact Email: •••••@•••••

  • Arizona Pulmonary Specialists

    RECRUITING

    Phoenix, Arizona, 85012, United States

    Contact Email: •••••@•••••

  • Bend Memorial Clinic

    RECRUITING

    Bend, Oregon, 97701, United States

    Contact Email: •••••@•••••

  • CHU de BICETRE SERVICE PNEUMOLOGIE

    RECRUITING

    Le Kremlin-Bicêtre, Val-de-Marne, 94275, France

    Contact Email: •••••@•••••

  • Fondazione IRCCS Policlinico San Matteo

    RECRUITING

    Pavia, Lombardy, 27100, Italy

    Contact Email: •••••@•••••

  • George Washington University Medical

    RECRUITING

    Washington D.C., District of Columbia, 20037, United States

    Contact Email: •••••@•••••

  • Hospital Universitario 12 de Octubre

    RECRUITING

    Madrid, Madrid, 28041, Spain

    Contact Email: •••••@•••••

  • Hospital Universitario de Toledo

    RECRUITING

    Toledo, Toledo, 45007, Spain

    Contact Email: •••••@•••••

  • Houston Methodist Hospital

    RECRUITING

    Houston, Texas, 77030, United States

    Contact Email: •••••@•••••

  • London Health Ontario

    RECRUITING

    London, Ontario, N6A 5W9, Canada

    Contact Email: •••••@•••••

  • Mayo Clinic of Florida

    RECRUITING

    Jacksonville, Florida, 32224, United States

    Contact Email: •••••@•••••

  • Medizinische Hochschule Hannover

    RECRUITING

    Hanover, Lower Saxony, 30625, Germany

    Contact Email: •••••@•••••

  • Ohio State University

    RECRUITING

    Columbus, Ohio, 43210, United States

    Contact Email: •••••@•••••

  • Pauls Stradins Clinical University Hospital

    RECRUITING

    Riga, LV-1002, Latvia

    Contact Email: •••••@•••••

  • Peter Lougheed Centre

    RECRUITING

    Calgary, Alberta, T1Y 6J4, Canada

    Contact Email: •••••@•••••

  • Policlinico Riuniti di Foggia

    RECRUITING

    Foggia, Apulia, 71122, Italy

    Contact Email: •••••@•••••

  • Pulmonary Hypertension Research Queensland

    RECRUITING

    Auchenflower, Queensland, 4066, Australia

    Contact Email: •••••@•••••

  • Royal Prince Alfred Hospital

    RECRUITING

    Camperdown, New South Wales, 2050, Australia

    Contact Email: •••••@•••••

  • Temple University

    RECRUITING

    Philadelphia, Pennsylvania, 19140, United States

    Contact Email: •••••@•••••

  • The University of Kansas Medical Center Research Institute

    RECRUITING

    Kansas City, Kansas, 66160, United States

    Contact Email: •••••@•••••

  • University of California Davis Health

    RECRUITING

    Rancho Cordova, California, 95670, United States

    Contact Email: •••••@•••••

  • University of Colorado

    RECRUITING

    Aurora, Colorado, 80045, United States

    Contact Email: •••••@•••••

  • University of Michigan

    RECRUITING

    Ann Arbor, Michigan, 48109, United States

    Contact Email: •••••@•••••

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