New pill hopes to ease breathing in rare lung conditions

NCT ID NCT07175038

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests an experimental oral drug called ROC-101 in 40 adults with pulmonary arterial hypertension (PAH) or pulmonary hypertension linked to interstitial lung disease (ILD-PH). Participants take the drug alongside their standard care for 24 weeks, with a long-term follow-up. The main goal is to see if the drug safely improves blood flow in the lungs and reduces symptoms like shortness of breath.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

hereditary sensory and autonomic neuropathy interstitial lung disease pulmonary arterial hypertension pulmonary hypertension pulmonary hypertension owing to lung disease and/or hypoxia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Arizona Pulmonary Specialists

    RECRUITING

    Phoenix, Arizona, 85012, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Bend Memorial Clinic

    RECRUITING

    Bend, Oregon, 97701, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CHU de BICETRE SERVICE PNEUMOLOGIE

    RECRUITING

    Le Kremlin-Bicêtre, Val-de-Marne, 94275, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Fondazione IRCCS Policlinico San Matteo

    RECRUITING

    Pavia, Lombardy, 27100, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • George Washington University Medical

    RECRUITING

    Washington D.C., District of Columbia, 20037, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hospital Universitario 12 de Octubre

    RECRUITING

    Madrid, Madrid, 28041, Spain

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • London Health Ontario

    RECRUITING

    London, Ontario, N6A 5W9, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Mayo Clinic of Florida

    RECRUITING

    Jacksonville, Florida, 32224, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Medizinische Hochschule Hannover

    RECRUITING

    Hanover, Lower Saxony, 30625, Germany

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Ohio State University

    RECRUITING

    Columbus, Ohio, 43210, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Pauls Stradins Clinical University Hospital

    RECRUITING

    Riga, LV-1002, Latvia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Peter Lougheed Centre

    RECRUITING

    Calgary, Alberta, T1Y 6J4, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Pulmonary Hypertension Research Queensland

    RECRUITING

    Auchenflower, Queensland, 4066, Australia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Royal Prince Alfred Hospital

    RECRUITING

    Camperdown, New South Wales, 2050, Australia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Temple University

    RECRUITING

    Philadelphia, Pennsylvania, 19140, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The University of Kansas Medical Center Research Institute

    RECRUITING

    Kansas City, Kansas, 66160, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of California Davis Health

    RECRUITING

    Rancho Cordova, California, 95670, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Colorado

    RECRUITING

    Aurora, Colorado, 80045, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Michigan

    RECRUITING

    Ann Arbor, Michigan, 48109, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••