PULMONARY ARTERIAL HYPERTENSION (PAH)
Clinical trials for PULMONARY ARTERIAL HYPERTENSION (PAH) explained in plain language.
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New injection tested to boost heart power in lung pressure disease
Disease control Not yet recruitingThis study is testing if adding an injectable medication called Treprostinil to a patient's existing oral therapy can improve heart function in people with intermediate-risk pulmonary arterial hypertension (PAH). All 32 participants will receive the injection for 3 months while r…
Matched conditions: PULMONARY ARTERIAL HYPERTENSION (PAH)
Phase: PHASE2 • Sponsor: Shanghai Zhongshan Hospital • Aim: Disease control
Last updated Apr 01, 2026 14:41 UTC
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Can a Heart-Lung pill fight a Parasite's Long-Term damage?
Disease control Not yet recruitingThis study aims to understand the long-term effects of a medication called selexipag for people with a specific type of high blood pressure in the lungs caused by a parasitic infection (schistosomiasis). Researchers will compare the health outcomes of about 30 patients who receiv…
Matched conditions: PULMONARY ARTERIAL HYPERTENSION (PAH)
Sponsor: Caio Júlio César dos Santos Fernandes • Aim: Disease control
Last updated Mar 31, 2026 12:12 UTC
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New hope for PAH patients: testing a novel drug to ease heart strain
Disease control Not yet recruitingThis study is testing an experimental drug called REGN13335 for adults with Pulmonary Arterial Hypertension (PAH), a serious lung and heart condition. The goal is to see if adding this new drug to a patient's current standard medications can better control the disease by reducing…
Matched conditions: PULMONARY ARTERIAL HYPERTENSION (PAH)
Phase: PHASE2 • Sponsor: Regeneron Pharmaceuticals • Aim: Disease control
Last updated Mar 30, 2026 14:34 UTC
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Could a pill replace daily inhalers for a serious lung condition?
Disease control Not yet recruitingThis study aims to understand if switching adults with pulmonary arterial hypertension (PAH) from a medication they inhale several times a day to a pill taken twice daily improves their quality of life and makes it easier to stick with treatment. Researchers will follow 32 patien…
Matched conditions: PULMONARY ARTERIAL HYPERTENSION (PAH)
Sponsor: University of Sao Paulo General Hospital • Aim: Disease control
Last updated Mar 25, 2026 14:09 UTC
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Groundbreaking stem cell trial aims to save tiniest Babies' lungs
Disease control Not yet recruitingThis early-stage study is testing a new stem cell treatment called PNEUMOSTEM® in very premature babies who develop high blood pressure in their lungs soon after birth. Researchers will give a single dose of the cells directly into the windpipe to see if it is safe and if it can …
Matched conditions: PULMONARY ARTERIAL HYPERTENSION (PAH)
Phase: PHASE1 • Sponsor: Samsung Medical Center • Aim: Disease control
Last updated Mar 24, 2026 12:02 UTC
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New hope for a rare Heart-Lung disease: can a novel drug reverse damage?
Disease control Not yet recruitingThis study is testing if a new drug called sotatercept can reduce harmful tissue changes in the lungs and heart of people with pulmonary arterial hypertension (PAH), a rare and serious disease. Researchers will use advanced imaging scans to see if the drug helps control the disea…
Matched conditions: PULMONARY ARTERIAL HYPERTENSION (PAH)
Phase: PHASE1, PHASE2 • Sponsor: University Hospital, Brest • Aim: Disease control
Last updated Mar 24, 2026 12:01 UTC
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Dual-Drug attack on deadly lung pressure in High-Risk heart patients
Disease control Not yet recruitingThis study compares starting treatment with two oral medications versus one medication for people newly diagnosed with pulmonary arterial hypertension (PAH) who also have at least two other heart-related conditions like high blood pressure or diabetes. It aims to find the safest …
Matched conditions: PULMONARY ARTERIAL HYPERTENSION (PAH)
Phase: PHASE3 • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Disease control
Last updated Mar 23, 2026 15:19 UTC
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Three-Pronged attack on deadly lung pressure disease
Disease control Not yet recruitingThis study is testing whether starting treatment with three different medications right away can better control a serious lung blood vessel disease called pulmonary arterial hypertension (PAH). It will involve 25 adults newly diagnosed with PAH who will take the drug combination …
Matched conditions: PULMONARY ARTERIAL HYPERTENSION (PAH)
Phase: PHASE2 • Sponsor: Philipps University Marburg • Aim: Disease control
Last updated Mar 20, 2026 14:47 UTC
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Survey reveals where patients and families search for answers about serious lung condition
Knowledge-focused Not yet recruitingThis study aims to learn where patients with pulmonary hypertension and their caregivers look for health information and what topics they search for most. Researchers will survey 100 patients and 100 caregivers using a short questionnaire about their information sources, satisfac…
Matched conditions: PULMONARY ARTERIAL HYPERTENSION (PAH)
Sponsor: University of Sao Paulo General Hospital • Aim: Knowledge-focused
Last updated Apr 01, 2026 14:41 UTC
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Gene hunt launched for rare, deadly vascular duo
Knowledge-focused Not yet recruitingThis study aims to find the genetic clues that explain why some people with a rare liver blood vessel defect develop a dangerous lung pressure condition. Researchers will analyze DNA from patients with both conditions and their close family members. The long-term goal is to use t…
Matched conditions: PULMONARY ARTERIAL HYPERTENSION (PAH)
Sponsor: Prof. Valérie Mc Lin • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:32 UTC
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Searching for environmental clues to a rare, incurable lung disease
Knowledge-focused Not yet recruitingThis study aims to understand if environmental and occupational exposures play a role in causing pulmonary arterial hypertension (PAH), a rare and currently incurable disease. Researchers will compare 150 newly diagnosed patients with PAH to patients with a different form of lung…
Matched conditions: PULMONARY ARTERIAL HYPERTENSION (PAH)
Sponsor: Poitiers University Hospital • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:39 UTC