New PET scans reveal how experimental drug reshapes lung vessels in PAH

NCT ID NCT07357974

First seen Feb 01, 2026 · Last updated Jun 13, 2026 · Updated 25 times

Summary

This pilot study will use special PET/CT scans to see how the experimental drug sotatercept affects blood vessel remodeling in the lungs and heart of people with pulmonary arterial hypertension (PAH). About 15 adults with PAH will receive sotatercept and have imaging at the start and after 24 weeks. The goal is to measure changes in fibroblast activity and lung blood flow, not to treat symptoms directly.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for PULMONARY ARTERIAL HYPERTENSION (PAH) are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Chu Brest

    Brest, Finistere, 29200, France

    Contact

Conditions

Explore the condition pages connected to this study.