Scientists hunt for genes behind rare lung complication in liver bypass patients

NCT ID NCT07314814

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study aims to find genetic variants that may explain why some people with a rare liver bypass condition (congenital portosystemic shunt) develop a serious lung complication called portopulmonary hypertension. Researchers will analyze blood samples from 120 patients and their close relatives. The goal is to better understand the genetic risk factors, not to test a new treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could help identify patients at risk for portopulmonary hypertension earlier, allowing for proactive management.

What could go wrong

This is an observational genetic study, not a treatment trial. It may not find clear genetic links, and any future applications are far off.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

congenital portosystemic shunt pulmonary arterial hypertension

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University Hospitals Geneva / University of Geneva

    Geneva, Canton of Geneva, 1205, Switzerland