Can less radiation be just as effective for early breast cancer?

NCT ID NCT07757958

First seen Aug 11, 2026 · Last updated Aug 12, 2026 · Updated 1 time

Summary

This trial is testing whether treating only part of the breast with radiation is as effective as treating the whole breast in women with early-stage, low-risk breast cancer. Participants are women aged 40 and older who had breast-conserving surgery and did not have a sentinel lymph node biopsy. The study compares recurrence rates, side effects, and quality of life between the two radiation approaches over five years.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Radiation therapy (partial breast irradiation compared to whole breast irradiation)
What this could lead to
If partial breast irradiation works as well as whole breast irradiation, it could offer a shorter, more targeted treatment with fewer side effects for many women with early breast cancer.
What could go wrong
This is a large trial, but results are not yet available. Partial breast irradiation might not control cancer as effectively as whole breast irradiation in the long term, and individual outcomes may vary.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Samsung Medical Center

    Seoul, 05649, South Korea

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Other studies related to the condition(s) this trial covers.