Samsung Medical Center

This trial compares two anesthesia drugs—remimazolam and propofol—to see which one leads to less postoperative delirium (sudden confusion) in people undergoing brain surgery. Delirium is a common complication that can slow recovery. The study involves about 700 neurosurgery patie…

This phase 2 study tested a combination of two drugs, pembrolizumab and ramucirumab, in 26 people with advanced stomach or gastroesophageal junction cancer that had spread. The goal was to see if the combo could shrink tumors or slow the disease. Participants received both drugs …

This study tested a combination of proton beam radiotherapy followed by two drugs (Tecentriq and Avastin) in 63 adults with advanced liver cancer that had spread into the portal vein. The goal was to see if this approach could help control the cancer and improve survival. Partici…

This study tested the drug osimertinib (Tagrisso) in 73 patients with a specific type of lung cancer that had spread to the lining of the brain and spinal cord (leptomeningeal metastases). Patients took one 80 mg tablet daily. The goal was to see if the drug could improve overall…

This study tested whether personalized, automatic coaching messages based on continuous glucose monitor readings and mood assessments could help people with insulin-treated type 2 diabetes improve their blood sugar control. 46 adults participated over 12 weeks. The goal was to se…

This completed early trial tested a single intravenous dose of EN001 stem cells in 3 adults with Charcot-Marie-Tooth disease type 1E, a severe hereditary nerve disorder with no approved treatment. The main goal was to check safety, including infusion reactions, while also looking…

This study tested a powered hip exoskeleton for gait training in 32 people who had a stroke at least 3 months earlier. Participants used the device for 10 sessions over 5 weeks. The main goal was to check safety and see if walking speed improved.

This study tested a home-based therapy program that uses sensors to help children with cerebral palsy improve the use of their arms and hands. The therapy, called Tele-HABIT, involves structured play activities done at home under remote guidance. The trial included 29 children ag…

This study tested whether a mobile app helps cancer patients undergoing chemotherapy or radiation therapy report their symptoms more effectively. Over 200 participants used the app to track side effects for 8 weeks. The goal was to see if the app improves how patients recognize a…

This study tested a smartphone app that gives personalized advice for managing lymphedema (arm swelling) after breast cancer treatment. Fifty-eight adults with lymphedema used the app to track their arm measurements and get self-care tips. The goal was to see if the app was easy …

This study tested two different eye drop treatments for people with dry eye disease who were having cataract surgery. One group used a single medication (rebamipide), while the other used a combination of two medications (diquafosol and cyclosporine). The goal was to see which ap…

This study tested a wearable back support suit designed to reduce back pain in caregivers who lift and move patients. Thirty male caregivers at a hospital wore the suit for two weeks and compared it to a traditional back brace. The goal was to see if the high-tech suit could bett…

This study tested remimazolam against midazolam for sedation during diagnostic upper gastrointestinal endoscopy. 132 healthy adults participated, and researchers measured total procedure time and sedation success. The goal is to see if remimazolam provides faster and more effecti…

This study analyzed health records from over 229,000 people with newly diagnosed lung cancer in Korea to see if getting a brain MRI every year helps find cancer that has spread to the brain. The goal was to learn whether these scans catch brain metastases earlier, when they might…

This study looked at 1,811 patients aged 60-70 who had heart valve replacement surgery. Researchers compared different types of artificial valves to see if the valve type was linked to developing depression, anxiety, or sleep disorders later. The goal was to understand if the cho…

This study gathered medical information and tissue samples from 2,000 head and neck cancer patients in South Korea. The goal was to learn more about how the disease behaves in Asian populations, since most existing research comes from Western countries. By analyzing this data, re…

This study looked at over 133,000 adults with newly diagnosed type 2 diabetes who were smokers. Researchers wanted to see if switching from regular cigarettes to e-cigarettes could lower the risk of heart problems and diabetes complications. The study used health records to compa…

This study looked at medical records of over 21,000 adults with type 2 diabetes and COPD to see if a diabetes drug called SGLT2 inhibitor lowers the chance of getting lung cancer compared to an older drug, sulfonylurea. Researchers did not give anyone new medicine; they just anal…

This study looked at whether frailty can predict who survives cardiogenic shock, a life-threatening condition where the heart suddenly can't pump enough blood. Researchers analyzed data from over 200,000 adults admitted to intensive care units across South Korea. They found that …

This study reviewed the medical records of over 3,100 people who had surgery to remove esophageal cancer at a major hospital in South Korea. The goal was to learn about common complications after surgery and how long patients lived afterward. The findings can help doctors improve…

This study looked at 203 breast cancer survivors with lymphedema, a chronic arm swelling condition. Researchers compared how patients perceived their swelling with actual physical measurements and examined how this gap affected quality of life. The goal was to understand the emot…