Could a different anesthetic lower the risk of Post-Surgery confusion?

NCT ID NCT06115031

First seen Jun 30, 2026 · Last updated Jul 01, 2026 · Updated 1 time

Summary

This trial compares two anesthesia drugs—remimazolam and propofol—to see which one leads to less postoperative delirium (sudden confusion) in people undergoing brain surgery. Delirium is a common complication that can slow recovery. The study involves about 700 neurosurgery patients and checks for delirium twice a day after surgery using standard assessment tools.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

remimazolam

What this could lead to

If remimazolam causes less postoperative delirium than propofol, it could become a preferred anesthetic for neurosurgery, improving recovery and reducing complications.

What could go wrong

This is a single-center trial, and results may not apply to all hospitals or patient groups. The difference between drugs may be small or nonexistent.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Emergence Delirium

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Samsung Medical Center

    Seoul, Seoul, 06351, South Korea