Could a different anesthetic lower the risk of Post-Surgery confusion?

NCT ID NCT06115031

Completed Disease control Sponsor: Samsung Medical Center Source: ClinicalTrials.gov ↗

First seen Jun 30, 2026 · Last updated Jul 01, 2026 · Updated 1 time

Summary

This trial compares two anesthesia drugs—remimazolam and propofol—to see which one leads to less postoperative delirium (sudden confusion) in people undergoing brain surgery. Delirium is a common complication that can slow recovery. The study involves about 700 neurosurgery patients and checks for delirium twice a day after surgery using standard assessment tools.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: remimazolam
What this could lead to: If remimazolam causes less postoperative delirium than propofol, it could become a preferred anesthetic for neurosurgery, improving recovery and reducing complications.
What could go wrong: This is a single-center trial, and results may not apply to all hospitals or patient groups. The difference between drugs may be small or nonexistent.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Emergence Delirium

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

POSTOPERATIVE DELIRIUM

Contacts and locations

Locations

Samsung Medical Center

Seoul, Seoul, 06351, South Korea

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Other studies related to the condition(s) this trial covers.