Samsung Medical Center

This study tests a drug called patritumab deruxtecan in adults with advanced solid tumors that have a rare genetic change called an NRG1 fusion. The goal is to see if the drug can shrink tumors or stop them from growing. About 30 people will take part, and the study is currently …

This study looks at whether starting treatment early for hidden atrial fibrillation (a type of irregular heartbeat) can reduce the amount of time the heart is in this rhythm. About 520 adults with heart devices that detect these hidden episodes will be split into two groups: one …

This study tests a new drug combination for people with a type of blood cancer (B-cell lymphoma) that has come back or not responded to treatment and has spread to the brain or spinal cord. The experimental drug selinexor is added to a standard chemotherapy regimen to see if it w…

This study looks at whether people who had a heart attack but do not have heart failure can safely stop taking beta-blockers after at least one year. About 2,540 adults will be randomly assigned to either stop or continue the medication. The goal is to see if stopping is just as …

This study tests a new way of giving radiation called PULSAR, which delivers short, powerful proton beam pulses spaced weeks apart. The goal is to better control pancreatic tumors while reducing side effects. About 47 adults with locally advanced or limited spread pancreatic canc…

This study is for men whose prostate cancer has returned after surgery, shown by rising PSA levels. It compares a standard few weeks of radiation to a much shorter course (just a few days) to see if the shorter option works just as well with fewer side effects. The goal is to mak…

This study tests whether the drug osimertinib can stop or shrink small, hazy spots (called ground-glass nodules) in the lungs of people who have already had surgery for a type of lung cancer with a specific gene change (EGFR mutation). About 59 adults aged 30–75 will take one pil…

This study tests whether a smart glove can help people with brain disorders (like stroke or brain injury) improve arm and hand function from home. Forty adults with lasting arm weakness will either use the smart glove or do standard home exercises. The goal is to see if the glove…

This study tests a personalized form of brain stimulation (rTMS) to improve walking in people with Parkinson's disease. Researchers will tailor the stimulation target based on each patient's brain function, rather than using a one-size-fits-all approach. The trial involves 60 par…

This study is for adults with a rare condition called hemophagocytic lymphohistiocytosis (HLH), where the immune system becomes overactive and damages the body. Researchers will track 81 participants to better understand the disease and see how well treatments like steroids and c…

This study looks at whether a special heart scan (coronary CT angiography) is better than standard follow-up care for high-risk patients who have had a stent placed to open blocked arteries. About 3,500 adults aged 19 and older with complex heart conditions will be enrolled. The …

This study is creating a huge, organized database of up to 800,000 Korean patients with heart or brain blood vessel diseases. Researchers will collect medical history and follow patients for years to track their health outcomes. The goal is to understand how these diseases progre…

This study is for people with advanced head and neck cancer who are receiving standard immunotherapy and chemotherapy. Researchers want to understand why only about 15% of patients respond well to these treatments. By analyzing tumor and blood samples before and after treatment, …

This study aims to create and test a new way to set therapy goals for children in the pediatric intensive care unit (PICU). Researchers will first ask a group of experts to agree on the best methods, then try these methods with a small number of caregivers and hospital staff. The…

This study looks at 200 adults with sick sinus syndrome who need a pacemaker. Researchers want to see if pacing the heart from the Bachmann bundle (a natural electrical pathway) is better for heart health than the usual pacing spot (right atrial appendage). Participants will have…

This study looks at whether the type of anesthesia given during lung cancer surgery can influence whether the cancer comes back. About 5,384 people having surgery to remove non-small cell lung cancer will be randomly assigned to receive either inhaled gas anesthesia or intravenou…