New pacemaker technique aims to protect heart function

NCT ID NCT07464041

Ongoing Disease control Sponsor: Samsung Medical Center Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jul 29, 2026 · Updated 3 times

Summary

This study compares a newer pacemaker method, left bundle branch area pacing (LBBAP), to the standard right ventricular pacing in 200 patients with heart block and normal heart function. The goal is to see if LBBAP better preserves the heart's pumping ability and reduces complications like heart failure. Participants will be randomly assigned to one of the two pacing methods and followed over time.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Left bundle branch area pacing (a type of pacemaker lead placement)
What this could lead to: If successful, this could show that a newer pacing method preserves heart function better than the standard approach, potentially reducing the risk of heart failure.
What could go wrong: This is a relatively early comparison study with 200 participants, and the benefits may not be large or apply to all patients. There is also a risk of lead dislodgement or other complications with the new pacing method.

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Conditions

The condition(s) this trial relates to.

atrioventricular block conduction system disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ATRIOVENTRICULAR BLOCK CONDUCTION SYSTEM PACING LEFT BUNDE BRANCH AREA PACING

Contacts and locations

Locations

Samsung Changwon Hospital

Changwon, South Korea
Samsung Medical Center

Seoul, Seoul, 06351, South Korea
Veterans Health Service Medical Center

Seoul, South Korea
Wonju Severance Christian Hospital

Wŏnju, Gangwon-do, South Korea

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