Could a simple inhaler shield lungs during cancer surgery?
NCT ID NCT04536675
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This phase 3 trial tests whether a daily inhaler containing two bronchodilators (vilanterol and umeclidinium) can help preserve lung function and improve quality of life in people with mild-to-moderate COPD who are undergoing lung cancer surgery. About 204 participants will use the inhaler or a placebo for at least 2 weeks before surgery and 16 weeks after. The main goal is to see if the treatment prevents the expected drop in lung function after surgery.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Vilanterol and Umeclidinium Bromide (daily inhaler)
What this could lead to
If it works, this could help people with mild-to-moderate COPD maintain better lung function and quality of life after lung cancer surgery.
What could go wrong
This is a relatively small, early-phase trial focused on a specific group (COPD patients having lung cancer surgery). The results may not apply to others, and the benefit over placebo may be modest.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Samsung Medical Center
Seoul, South Korea