Can MRI outperform ultrasound for breast cancer screening in dense breasts?

NCT ID NCT05797545

Ongoing Diagnosis Sponsor: Samsung Medical Center Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares breast ultrasound with two types of breast MRI (abbreviated and full protocol) for detecting new breast cancers in women who have dense breasts and a personal history of breast cancer. About 1,756 women will be randomly assigned to one of the screening methods. The goal is to see which test finds more cancers and has fewer false alarms.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could show that abbreviated MRI is better than ultrasound for finding new breast cancers in women with dense breasts, leading to improved screening guidelines.
What could go wrong: This is a diagnostic comparison study, not a treatment trial. It may find that MRI detects more cancers but also leads to more false alarms or is less practical due to cost and availability.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BREAST CANCER BREAST NEOPLASMS

Contacts and locations

Locations

Inje University Busan Paik Hospital

Busan, BusanJin-Gu, 47392, South Korea
Samsung Medical center

Seoul, Gangnam-gu, 06351, South Korea
Soon Chun Hyang University Hospital Seoul

Seoul, Yongsan-Gu, 04401, South Korea

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