Precision radiation and immunotherapy join forces against inoperable stomach cancer

NCT ID NCT07607119

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study is testing a new way to give radiation therapy (called PULSAR) along with standard chemotherapy and immunotherapy for people with advanced stomach cancer that cannot be removed with surgery. The radiation is given in high doses every few weeks, tailored to each patient's tumor. The goal is to see if this combination can stop the cancer from growing for at least a year. The study plans to enroll 53 adults with a specific type of stomach cancer (HER2-negative, EBV-negative, and microsatellite stable).

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

PULSAR (personalized radiation therapy) combined with immunotherapy and standard systemic therapy

What this could lead to

If successful, this could offer a new treatment option for people with advanced gastric cancer that cannot be removed by surgery, potentially delaying disease progression.

What could go wrong

This is a small, early-phase study (53 people) at a single center, so results may not apply broadly. The combination of radiation and immunotherapy may cause side effects, and it is not yet known if it will improve survival.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

gastric adenocarcinoma gastric cancer gastric neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Samsung Medical Center

    RECRUITING

    Seoul, Select Province/State, 06351, South Korea

    Contact Phone: •••-•••-•••• Email: •••••@•••••