Precision radiation and immunotherapy join forces against inoperable stomach cancer
NCT ID NCT07607119
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This study is testing a new way to give radiation therapy (called PULSAR) along with standard chemotherapy and immunotherapy for people with advanced stomach cancer that cannot be removed with surgery. The radiation is given in high doses every few weeks, tailored to each patient's tumor. The goal is to see if this combination can stop the cancer from growing for at least a year. The study plans to enroll 53 adults with a specific type of stomach cancer (HER2-negative, EBV-negative, and microsatellite stable).
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- PULSAR (personalized radiation therapy) combined with immunotherapy and standard systemic therapy
- What this could lead to
- If successful, this could offer a new treatment option for people with advanced gastric cancer that cannot be removed by surgery, potentially delaying disease progression.
- What could go wrong
- This is a small, early-phase study (53 people) at a single center, so results may not apply broadly. The combination of radiation and immunotherapy may cause side effects, and it is not yet known if it will improve survival.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for GASTRIC ADENOCARCINOMA are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Samsung Medical Center
RECRUITINGSeoul, Select Province/State, 06351, South Korea
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can AI-Guided home training boost recovery from gastric cancer surgery?
- Can a new drug combo shrink Hard-to-Treat tumors?
- Can immunotherapy outperform chemo after stomach cancer surgery?
- Could a smartphone program supervised by AI boost recovery after stomach cancer surgery?
- Can stomach cancer surgery also tame diabetes?
- Can a modified stomach bypass speed up recovery in advanced gastric cancer?