New combo aims to supercharge immune cells against blood cancers

NCT ID NCT05044039

First seen Dec 16, 2025 · Last updated May 14, 2026 · Updated 22 times

Summary

This early-phase study tests whether adding the drug duvelisib after CAR T-cell therapy can help the immune cells stay active longer and reduce side effects like cytokine release syndrome. About 42 adults with non-Hodgkin lymphoma or acute lymphocytic leukemia will take part. The goal is to find a safe dose and see if this approach improves cancer control.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Washington University School of Medicine

    St Louis, Missouri, 63110, United States

Conditions

Explore the condition pages connected to this study.