New combo therapy targets tough pancreatic cancer

NCT ID NCT04331041

First seen Oct 31, 2025 · Last updated Apr 28, 2026 · Updated 29 times

Summary

This study tests whether adding a drug called defactinib (a FAK inhibitor) to precise, high-dose radiation therapy can help control advanced pancreatic cancer better than radiation alone. About 42 people with locally advanced, inoperable pancreatic cancer will take part. The main goal is to see if the combination slows cancer growth or improves survival.

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Contacts and locations

Locations

  • Washington University School of Medicine

    St Louis, Missouri, 63110, United States

Conditions

Explore the condition pages connected to this study.