Which diet wins? study tests mediterranean, Low-Carb, and Plant-Based plans on obesity

NCT ID NCT02706262

Ongoing Knowledge-focused Sponsor: Washington University School of Medicine Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at why some people with obesity develop conditions like type 2 diabetes while others don't. Researchers are comparing three popular diets—Mediterranean, low-carb, and very-low-fat plant-based—in 180 participants to see how they affect insulin sensitivity and overall health. The goal is to understand which diet works best for improving metabolic function.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Mediterranean diet, low-carbohydrate diet, very-low-fat plant-based diet
What this could lead to: If successful, this study could help identify which diet is best for improving insulin sensitivity and reducing obesity-related health risks.
What could go wrong: This is an observational dietary study, not a treatment trial. Results may not apply to everyone, and dietary adherence can vary widely.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Insulin Resistance Obesity obesity disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

INSULIN RESISTANCE OBESITY

Contacts and locations

Locations

Washington University School of Medicine

St Louis, Missouri, 63110, United States

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