Double transplant strategy targets tough lymphoma

NCT ID NCT00882895

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase 2 study tests a two-step transplant approach for people with high-risk non-Hodgkin's lymphoma. First, patients receive a transplant using their own stem cells, followed by a second transplant from a donor. The goal is to improve long-term disease control. The trial enrolled 18 adults aged 18 to 70 with aggressive or relapsed lymphoma.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

stem cell transplant (autologous followed by non-myeloablative allogeneic)

What this could lead to

If it works, this two-step transplant approach could offer better long-term control of high-risk non-Hodgkin's lymphoma.

What could go wrong

This is a small, early-phase trial with only 18 participants, so results may not apply broadly. The procedure carries risks like graft-versus-host disease and infection.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

lymphoma, non-Hodgkin, familial non-Hodgkin lymphoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Washington University

    St Louis, Missouri, 63110, United States