University Hospital, Strasbourg, France

This study looks at whether a single surgery to replace an infected hip or knee joint works as well as the usual two-step approach for rare Candida fungal infections. Researchers will check infection clearance in 16 adults who had this one-stage procedure. The goal is to see if o…

This study looks at 830 people with relapsing-remitting multiple sclerosis (MS) that started after age 50. Researchers compare two treatment strategies: starting with a moderate medication and switching if needed, versus starting with a stronger medication right away. The goal is…

This study looks at whether sleep disorders make vertigo worse for people with Ménière's disease, a condition that causes hearing loss, ringing in the ears, and dizziness. Researchers will follow 100 adults from a French hospital to see if those with more severe vertigo also have…

This study surveys 269 healthcare professionals in Alsace, France—including psychiatrists, midwives, and general practitioners—to assess their knowledge and practices regarding eating disorders during pregnancy and the postpartum period. The goal is to identify gaps in care and i…

This study aims to find out how many adults with cystic fibrosis smoke or vape, either actively or passively. Researchers will survey 100 adults who get regular care at a specialized center in France. The goal is to gather current data to improve tobacco prevention and understand…

This study reviews medical records of 221 people with advanced melanoma who received immunotherapy between 2013 and 2021. The goal is to find new clues that predict who will have a complete response, meaning their cancer disappears entirely. By understanding these factors, doctor…

This study looks at how different types of platelets (blood cells that help clotting) change in adults who need a heart-lung machine (ECMO) for severe heart or lung failure. Researchers will take blood samples on days 1, 3, and 7 after starting ECMO to see if shifts in platelet t…

This study examines whether taking metformin before being admitted to the intensive care unit (ICU) with severe lactic acidosis affects a patient's chances of survival. Researchers will review records of 100 adults with type 2 diabetes who were admitted to a French hospital ICU b…

This study looks at 50 adults with unexplained bleeding to see if low serotonin levels in their platelets are linked to their condition. Researchers will use a standard bleeding questionnaire to measure symptoms. The goal is to better understand how serotonin affects bleeding ris…

This study reviews medical records of 400 adults hospitalized with a severe strep blood infection (Streptococcus anginosus group). The goal is to identify factors linked to death within 28 days. No new treatments are tested; the aim is to learn from past cases to improve future c…

This study looks back at the medical records of 400 full-term newborns who had very low cord blood pH (below 7.00) at birth, a sign of severe oxygen shortage. Researchers want to find patterns in fetal heart rate recordings that can help doctors spot when a baby is struggling ear…

This study looks at whether surgical or medical abortion causes more heavy bleeding (over 500 cc) in women between 14 and 16 weeks pregnant. Researchers will observe 50 adults having an abortion at a French hospital. The goal is to help patients and doctors choose the safest meth…

This study looks at how well a certain type of knee replacement (a fixed polyethylene posteriorly stabilized cemented total knee prosthesis) works over at least one year. Researchers will review medical records and X-rays from about 960 adults who had this surgery between 2013 an…

This study looks at whether high-speed centrifugation can remove excess fat from blood samples so that a key test (anti-Xa activity) works correctly. The test is used to monitor blood thinners, but fatty samples can give wrong results. Researchers will add fat to routine blood sa…

This study looks at blood clotting (hemostasis) in 1,000 premature infants born before 37 weeks. Researchers want to find out what normal clotting values are from birth to 18 months, and whether they differ from full-term babies. The goal is to help doctors better understand and …

This study looks at 100 patients in France who developed a severe form of Lyme disease after receiving anti-CD20 treatment (a type of medication that lowers the immune system). Researchers want to understand the symptoms, severity, and progression of the infection in these patien…

This study surveys 100 French dentists who treat children to understand their choices for managing non-vital baby teeth. It compares common extraction with alternatives like pulpectomy and LSTR. The goal is to collect data on current practices and decision-making criteria, not to…

This study aims to better understand Lewy body disease by examining brain activity patterns in 40 patients. Researchers will analyze EEG recordings to see if specific brain wave abnormalities are linked to this neurodegenerative condition. The goal is to improve understanding of …

This study looks at how doctors currently screen and treat obstructive sleep apnea (OSA) in children with Down syndrome. Researchers will review medical records of 30 children to see how well treatments work. The goal is to create a simple guide to improve care for these children…

This study looks at how sleep helps or hurts memory in children with certain types of epilepsy. Researchers will test memory in children with mild or severe epilepsy and compare them to children without epilepsy. The goal is to see if epileptic brain activity during sleep causes …

This study looks at 36 adults with type 1 diabetes who have received a pancreatic islet transplant. Researchers want to see if a continuous glucose monitor (CGM) can detect early loss of the transplanted cells' function. They will track a measure called "Time in Tight Range" (blo…

This study looks at why families refuse organ donation when asked, even though most people in France support it. Researchers will talk to families of 100 brain-dead patients in the ICU to understand their reasons. The goal is to reduce refusals and help more people get life-savin…

This study looks at real-life cases where adults with psychotic disorders try to lower or stop their antipsychotic drugs under careful monitoring. The goal is to learn when and how this can be done safely, balancing the risk of relapse with the desire to avoid side effects. Resea…

This study explores whether a fresh human placenta can be used as a realistic, low-cost training tool for neurosurgeons learning to repair brain aneurysms. Researchers will enroll 50 participants to practice microsurgery on placental vessels, which closely resemble brain blood ve…

This study looks at whether common blood thinners (heparins) can mess up lab tests for another blood thinner (argatroban). When doctors switch patients from one blood thinner to another, accurate testing is crucial to avoid bleeding or clotting risks. Researchers will analyze blo…

This study aims to understand if changes in a specific blood or lung fluid test (PCR) for a serious fungal infection can predict how well a patient will respond to treatment. Researchers will look back at medical records from 100 adults who had this test at a French hospital betw…

This study tests a new MRI method to find tiny brain changes in professional soccer players who may be at risk for chronic traumatic encephalopathy (CTE) from repeated headers. Researchers will compare brain scans of 80 male players nearing retirement or recently retired with tho…

This study reports on one adult with severe hemophilia A who is receiving long-term anticoagulation (blood thinners). Hemophilia A is a genetic bleeding disorder where blood does not clot properly. The goal is to share how this patient's clotting factor levels and bleeding risks …

This study looks at whether having knee replacement surgery as an outpatient (going home the same day) leads to better recovery compared to staying in the hospital. Researchers will measure recovery using a questionnaire called QoR-15F. About 440 adults who had knee replacement a…