University Hospital, Strasbourg, France

This study looks at a new way to fix a common elbow fracture in children using anchors with sutures instead of screws or pins. The goal is to reduce problems like hardware irritation and the need for a second surgery to remove implants. Nine children under 15 with displaced fract…

This study tests whether eating gradually increasing amounts of raw apple can help people with birch pollen and apple allergies tolerate the fruit. About 110 participants will receive oral immunotherapy for 9 months. The goal is to reduce or eliminate the mouth itching and swelli…

This study looks at whether replacing an infected hip or knee joint in a single surgery works as well as the usual two-step approach for a rare Candida fungal infection. Researchers will check if the infection clears up after one surgery combined with antifungal medicine. The stu…

This study looks at how well a non-surgical endoscopic procedure can repair bile duct injuries that happen during gallbladder or liver surgery. Researchers will track 220 adults to see how many have successful treatment right away and after 3 months. The goal is to find a less in…

This study looks at 550 adults having a heart procedure through the wrist. It compares giving heparin (a blood thinner) before inserting the tube versus after. The goal is to see if earlier heparin reduces the risk of the wrist artery becoming blocked.

This study looks at whether reducing immunosuppressive medications can help kidney transplant patients recover from life-threatening infections in the intensive care unit (ICU). About 212 adult kidney transplant recipients who are in the ICU with septic shock or severe breathing …

This study tests if freezing tumors (cryoablation) works better than standard drugs for people with desmoid tumors that keep growing after a watch-and-wait period. About 150 participants aged 13 and older will be randomly assigned to one of the two treatments. The goal is to stop…

This study looks at whether using one antibiotic or a combination of two antibiotics works better for a serious bloodstream infection caused by Enterococcus faecalis. The infection can be deadly, with a 15-25% death rate. Researchers will track 700 adults to see which approach lo…

This study looks at 830 people with relapsing-remitting multiple sclerosis (MS) that started after age 50. Researchers compare two treatment strategies: starting with a moderately effective drug versus starting with a highly effective drug. The goal is to see which approach bette…

This study is testing whether the antibiotic clindamycin works as well as other antibiotics for treating strep infections that occur around artificial joints (like hip or knee replacements). The researchers will compare success rates in 260 adults who had surgery for the infectio…

This study compares a new test called Cryocheck HexLA to current methods for detecting lupus anticoagulant, a substance that can increase blood clot risk. Researchers will analyze blood samples from 200 adults to see if the new test is more accurate and less affected by blood-thi…

This study looks at whether a simple decision-making flowchart can help general practitioners better diagnose and refer patients with vertigo. Researchers will compare the tool's diagnosis with that of an ear, nose, and throat specialist. The goal is to improve patient care and r…

This study looks at two simple checklists (PERC and YEARS) to see if they can safely rule out a blood clot in the lungs without needing a CT scan. Researchers will review records of 500 adults who came to the emergency room with possible clots. If these tools work well, they coul…

This study looks at a newer biopsy method called cryobiopsy, which uses freezing to take lung tissue samples. The goal is to see how safe and accurate it is for diagnosing conditions like interstitial lung disease and enlarged lymph nodes in the chest. About 30 adults who need th…

This study is testing whether specially trained dogs can detect bladder cancer by smelling urine samples. Researchers will collect urine from 340 adults scheduled for bladder surgery and see how often the dogs correctly identify cancer. If successful, this could lead to a new, no…

This study tests whether applying a gel made from a patient's own blood (platelet-rich fibrin) during disc surgery can prevent long-term nerve pain. About 60 adults having surgery for a herniated disc will take part. The gel is placed near the nerve root to reduce inflammation an…

This study looks at whether giving pregnant women free organic vegetables and healthy-eating workshops can reduce their exposure to pesticides. Researchers will compare urine pesticide levels in women who get the veggies versus those who eat as usual. The goal is to see if this s…

This study looks at two versions of a surgery (Nuss technique) for pectus excavatum, a condition where the chest is sunken inward. Researchers will compare the classic method with a modified one in 80 teens aged 11-18. They want to see which approach leads to shorter surgery, les…

This study tests if dialectical behavior therapy (DBT) can help people who have had a brain injury better manage emotions and reduce challenging behaviors. About 45 adults with a brain injury from at least 18 months ago will first receive usual care for 5 months, then DBT for 5 m…

This study tests whether a personalized facial rehabilitation program can improve mouth function and quality of life in people with systemic sclerosis (scleroderma) who have facial tightness and difficulty opening their mouth. About 60 adults will be assigned to either the rehab …

This study tests whether hearing their mother's voice can reduce pain in very premature babies during a common blood draw procedure (venipuncture). About 48 babies born before 32 weeks will be studied, comparing standard pain relief with added maternal voice contact. The goal is …

This study tests whether giving parents an easy-to-understand information sheet after their child's first simple febrile seizure reduces repeat emergency visits and eases anxiety. About 100 parents of children aged 9 months to 5 years will receive the sheet during their first ER …

This study looks back at medical records of 100 adults diagnosed with human babesiosis in France between 2000 and 2024. Babesiosis is a rare tick-borne infection that can be severe in people with weak immune systems, no spleen, or older age. The goal is to describe how the diseas…

This study looks at whether certain medications that alter gut bacteria can influence how well immunotherapy works in people with advanced lung cancer. Researchers will review medical records from 800 adults to see if these drugs affect survival. The goal is to find ways to impro…

This study looks at how fast blood thinners start working in ICU patients with serious lung clots (pulmonary embolism). Researchers will review past records of 100 adults to measure the time it takes to reach effective levels and see if faster treatment reduces deaths, prevents n…

This study surveys 100 doctors and medical trainees in France to see how much they know about tick-borne encephalitis, a rare but serious brain infection spread by ticks. The goal is to find gaps in knowledge so that diagnosis and prevention can be improved, especially in areas w…

This study is testing whether a short questionnaire (the SCST score) is easy for patients to use and useful for doctors to track allergic rhinitis (hay fever) severity over time. About 30 adults with allergic rhinitis will fill out the form during their ENT visits. The goal is to…

This study looks at whether common blood thinners (heparins) can mess up lab tests for another blood thinner called argatroban. Doctors often switch patients from heparin to argatroban, but current tests might not tell the two apart, risking bleeding or clots. Researchers will an…

This study will count how many adults with cystic fibrosis smoke or vape. Researchers want to understand the real situation so they can improve prevention and see how smoking affects newer treatments. About 100 adults from one French center will take part.

This study collects information from about 100 adults in Alsace who have had a confirmed case of human anaplasmosis, a bacterial infection spread by ticks. Researchers want to learn more about how common it is, what symptoms people have, and how serious it can be. The goal is to …

This study looks at cases of severe Lyme disease (disseminated borreliosis) in patients who have received anti-CD20 therapy, a type of immune-suppressing treatment. Researchers want to describe the symptoms, severity, and progression of the infection in these patients. The study …

This study looks at why some people with advanced bladder cancer receive older platinum-based chemotherapy instead of a newer, more effective drug combination. Researchers will review the medical records of 50 patients to understand the reasons behind these treatment choices. The…

This study looks back at 100 adults treated at Strasbourg University Hospital between 2014 and 2023 for a rare condition where an abnormal connection forms between the airway and digestive tract. The goal is to learn how these patients were managed and what their survival rates w…

This study aims to understand why families refuse organ donation when asked, even though most people support it. Researchers will talk to families of 100 brain-dead patients in a French hospital to learn their reasons. The goal is to reduce refusals and help more people get life-…

This study looks at how people feel and function after surviving a severe abdominal emergency called acute mesenteric ischemia. Researchers will ask 100 adults treated at Strasbourg University Hospitals between 2010 and 2022 to fill out a quality-of-life questionnaire. The goal i…

This study tests a new DNA reading technology (long-read sequencing) to find genetic causes of dystonia—a movement disorder causing muscle spasms—in 150 people whose standard genetic tests came back normal. By reading longer DNA segments, researchers hope to uncover hidden geneti…

This study looks at people with systemic scleroderma who also have a family member with the disease. Researchers want to understand how the disease runs in families and find clues that could lead to better treatments. About 20 adults will take part, and no new treatments are bein…

This study looks at adults aged 75 and older who come to the emergency room with a medical problem and need to be admitted to the hospital. Researchers want to see if patients who first go to a short-stay unit have different survival rates after three months compared to those adm…

This study looks at how fatigue and muscle function are connected in people with axial spondyloarthritis, a type of inflammatory arthritis affecting the spine. Researchers will measure exercise capacity and muscle strength in 122 adults starting a new targeted therapy. The goal i…

This study looks at 50 adults with unexplained bleeding to understand how low serotonin levels in platelets affect blood clotting. Researchers will use a bleeding questionnaire to measure symptoms. The goal is to gather knowledge, not to test a new treatment.

This study looks at whether continuously monitoring oxygen levels while moving patients from the operating room to the recovery area can prevent dangerous drops in oxygen. About 30 adults having surgery will take part. Researchers will compare oxygen readings taken at the start a…

This study tests whether a questionnaire called AT HARM 10 can help identify emergency room visits caused by medication problems in adults over 65. Researchers will check 100 patients at one hospital to see how often these drug-related issues occur. The goal is to improve medicat…

This study looks back at medical records of 221 people with advanced melanoma who received immunotherapy between 2013 and 2021. The goal is to find new clues that predict who will have a complete response, meaning their cancer disappears entirely. By understanding these factors, …

This study tests whether a special CT scan (dual-energy CT) can be as accurate as MRI for staging mouth and throat cancers. About 30 adults with these cancers will get both scans, and researchers will compare the results. If the CT works just as well, it could speed up treatment …

This study interviews 15 doctors in Alsace, France, who treat elderly patients with osteoporosis and have used a practical guide on the condition. The goal is to find out what helps or prevents them from using the guide in their daily practice. By understanding these factors, res…

This study looks at how blood cells work and levels of oxidative stress in 120 people with pre-capillary pulmonary hypertension. Researchers want to see if these blood markers can help detect the disease and predict how it will progress. Participants give blood samples during rou…

This study looks back at 2,450 women who had C-sections at Strasbourg University Hospital to understand why some still feel pain despite spinal anesthesia. Researchers will identify risk factors and how doctors managed the pain. The goal is to create a better prevention and treat…

This study interviews 12 general practitioners in Bas-Rhin, France to find out what makes it hard to care for terminally ill patients at home. Many people want to die at home, but doctors face obstacles like heavy workloads and emotional strain. The goal is to understand these ba…

This study aims to describe a rare condition called panniculitis (inflammation of the fat under the skin) in people with dermatomyositis. Researchers will examine 20 participants aged 1 year and older to identify unique clinical and microscopic features. The goal is to better dis…

This study looks at blood clotting test results from up to 1,000 premature infants (born before 37 weeks) to find what's normal for them from birth to 18 months old. Researchers want to see if these values differ from full-term babies. The study only uses existing lab samples and…

This study looks at whether surgical or medical abortion causes more heavy bleeding in women between 14 and 16 weeks pregnant. Researchers will track blood loss in 50 women to help doctors and patients choose the safest method. The goal is to improve care after France extended th…

This study looks at whether sleep disorders are linked to more severe vertigo in people with Ménière's disease, a condition that causes hearing loss, ringing in the ears, and dizziness. Researchers will track 100 adults from a French hospital to see if those with worse sleep also…

This study looks at 500 adults who had total knee replacement surgery to see if spinal anesthesia leads to better recovery than general anesthesia. Recovery is measured using a questionnaire called QoR-15F. The goal is to find out which method helps patients feel better sooner af…

This study looks back at medical records of 50 adults in France who were diagnosed with HIV between 2021 and 2024. Researchers want to find out if doctors missed signs of HIV during visits in the year before diagnosis. The goal is to understand why testing is delayed and help cat…

This study looks at how many women with Turner syndrome who want to become parents actually succeed, whether through natural pregnancy, egg donation, or adoption. Researchers will review medical records of 93 adult women treated at a French hospital between 2009 and 2019. The goa…

This study looks at whether a continuous glucose monitor (CGM) can help detect early loss of function in transplanted pancreatic islet cells. Researchers will track 36 adults with type 1 diabetes who have already received an islet transplant. The goal is to see if a drop in "time…

This study looks back at medical records of 60 adults treated for adrenal cortex carcinoma (ACC), a rare adrenal gland tumor. Researchers want to understand the disease better by analyzing patients' symptoms, test results, and survival over time. The goal is to improve how doctor…

This study looks at a scoring tool called the HScore to see how well it can diagnose a rare overactive immune condition (HLH) in intensive care patients who also have liver failure or cirrhosis. Researchers will review medical records of 100 adults admitted to one hospital over t…

This study looks at 100 children under 18 who come to the emergency room with visible blood in their urine. The goal is to find out what causes this symptom and how doctors currently manage it. No new treatments are being tested; instead, researchers hope to create a standard car…

This study looks at whether measuring Aspergillus fumigatus DNA in blood or lung fluid can help predict outcomes in patients with invasive aspergillosis, a serious fungal lung infection. Researchers will track 100 adults to see if changes in PCR levels during treatment relate to …

This study looks at a special ultrasound technique called liver elastography to measure liver scarring in children with type III glycogen storage disease. The goal is to see if this painless scan can replace the need for a liver biopsy. Researchers will review past scans from 30 …

This study looks at how sleep helps or hurts memory in children with certain types of epilepsy. Researchers will test memory before and after sleep in 95 children with epilepsy and compare them to children without epilepsy. The goal is to see if epileptic brain activity during sl…

This study will review the medical records of about 115 transgender people who started medical support before age 18 at Strasbourg University Hospital. The goal is to describe the care they received and their health outcomes. No new treatments are being tested; instead, researche…

This study looks at one adult with severe hemophilia A who is taking long-term blood thinners (anticoagulation). The goal is to understand how to balance bleeding risks from the blood thinner with the natural protection against clots from hemophilia. Newer clotting factor treatme…

This study looks at medical records of 20 adults who had bariatric surgery and later received treatment for alcohol use disorder. Researchers want to understand how the surgery was considered during addiction follow-up. The goal is to improve care for patients with both condition…

This study looks at how a stay in the intensive care unit (ICU) affects a person's quality of life and risk of post-traumatic stress disorder (PTSD). Researchers will ask 40 adults who spent more than 48 hours in the ICU to fill out questionnaires about their experience and curre…

This study looks at 100 adults with type 2 diabetes who were admitted to the ICU with severe lactic acidosis. Researchers want to see if taking metformin before admission affects their chances of survival. The goal is to better understand the role of this common diabetes drug in …

This study looks at whether high-speed centrifugation (spinning blood very fast) can remove fat from blood samples so doctors can accurately measure anti-Xa activity, a test used to monitor blood thinners. About 150 adults on anticoagulants will have their blood samples tested. T…

This study looks at how doctors treat severe stomach or intestinal bleeding in patients who take blood thinners (DOACs). Researchers will review the records of 250 adults admitted to the emergency room to see how often a drug called prothrombin complex concentrate is used to reve…

This study reviews medical records of 400 adults hospitalized with a serious strep blood infection (Streptococcus anginosus). The goal is to identify factors linked to death within 28 days. No new treatments are tested; instead, researchers hope to learn what makes this infection…

This study surveys 269 healthcare professionals in Alsace, France, including psychiatrists, midwives, and general practitioners, to understand their knowledge and practices around eating disorders during pregnancy and the postpartum period. The goal is to identify gaps in care an…

This study explores using donated human placentas as a realistic, low-cost training tool for neurosurgeons learning to repair brain aneurysms. About 50 placentas will be used to assess surgical skill improvement. The goal is to provide hands-on practice without relying on animals…

This study looks at how flexible brain activity is in people with Lewy body disease, a condition that causes thinking and behavior problems. Researchers will analyze past EEG tests from 40 adults to see if certain brain patterns are linked to the disease. The goal is to better un…

This study looks at whether having total knee replacement surgery as an outpatient (going home the same day) leads to better recovery compared to staying in the hospital overnight. Researchers will review medical records of 440 adults who had knee replacement at a French hospital…

This study looks at 30 adults with psychotic disorders who are stable on long-term antipsychotics and want to reduce or stop their medication. Researchers will describe each person's experience, including what worked and what didn't, to help doctors learn when and how to safely d…

This study looks at how the way doctors talk about breech birth affects a mother's choice between vaginal delivery and C-section. Researchers will survey 200 women who gave birth to a breech baby in 2024 at French university hospitals, along with their doctors. The goal is to und…

This study surveys 100 healthcare professionals and students in Alsace, France, to understand their training, knowledge, and experience with organ donation. The goal is to find out if current training is sufficient, clear, and useful, and to identify misconceptions that may hinde…

This study looks at children whose parents had an extra genetic test (exome sequencing) during pregnancy because of ultrasound findings. Researchers want to see how these children develop after birth, especially when the test results were negative. The goal is to learn whether a …

This study looks at how often newborns who fail their hearing test have a hidden infection called cytomegalovirus (CMV). CMV is a common virus that can cause hearing loss and other health problems. The goal is to collect data to improve screening and follow-up care for these babi…

This study looks at whether medical students in their final year find it acceptable to receive training on how to certify a death and how to tell a family that their loved one has died. Twenty students from the University of Strasbourg will be asked about their views. The goal is…

This study looks at how well a particular type of knee replacement works in 960 adults who had surgery between 2013 and 2024. Researchers will check knee function and X-ray results at least one year after surgery. The goal is to see how the prosthesis performs and compare it to o…

This study surveys 50 pregnant women at the CMCO to understand their interest in and fears about ambulatory (walking) epidural anesthesia, a technique that allows more movement during labor. The goal is to learn what patients expect and worry about before the hospital introduces …

This study looks at whether nutritional status is linked to prognosis in adults with gastroenteropancreatic neuroendocrine tumors (NETs), which are slow-growing cancers of the digestive system. Researchers will assess malnutrition in 100 participants aged 18 to 70 who have been t…

This study looks back at how often and why antithrombin—a blood protein that helps prevent clots—was given to patients in intensive care or during surgery at Strasbourg University Hospitals over one year. Researchers will review records of 160 adults who received it to see if pre…

This study looks back at how doctors currently screen for and treat obstructive sleep apnea (OSA) in children with Down syndrome. Researchers will review medical records of 30 children to see what works and what doesn't. The goal is to create a standard guide to improve care acro…

This study looks at how occupational health doctors and nurses in France identify police officers who may be struggling with mental health issues like depression, anxiety, or PTSD, and how they refer them to specialized care. About 200 health professionals who work with national …

This study looks at chest CT scans from 80 patients with a rare but serious fungal lung infection called pulmonary mucormycosis. Researchers want to see if certain patterns on the scans can predict whether a patient will get better or worse. The goal is to help doctors tailor fol…

This study examines how patients who have had a transient ischemic attack (TIA), or mini-stroke, are diagnosed and treated in the emergency department. Researchers will review records of 300 adults to see if care matches their risk level. The goal is to find gaps in current pract…

This study looks at whether teaching delivery room staff how to better find and repair tears in the anal muscles during childbirth can lower the number of women who later have trouble controlling gas or stool. About 1,000 women who gave birth vaginally at a French hospital will b…

This study tests a special MRI technique to spot tiny brain changes in professional soccer players near retirement. Researchers will compare their scans to people who never played contact sports. The goal is to catch early signs of chronic traumatic encephalopathy (CTE) and impro…

This study uses questionnaires to find out what teenage girls (ages 11-18) with hypogonadism and their parents know about hormone replacement therapy. The goal is to identify gaps in understanding so that better educational programs can be created to help patients stick with thei…

This study looks at whether people who are more physically active before incisional hernia surgery have fewer problems afterward. Researchers will track 100 adults who already had the surgery and see if their activity level relates to complications. The goal is to understand if b…

This study looks back at the medical records of 30 immunocompromised patients (like organ transplant recipients or those on immune-suppressing drugs) who had toxoplasmosis. The goal is to understand how many are affected and how to better diagnose, treat, and prevent this infecti…

This study surveys 100 French dentists who treat children to understand how they handle baby teeth with irreversible pulpitis or pulp necrosis. The goal is to collect information on whether they choose extraction, pulpectomy, or other methods, and what factors influence their dec…

This study looks at cases of recurrent borreliosis, a bacterial infection spread by ticks or lice, that have been diagnosed in France. Researchers will describe the symptoms, where patients got infected, which Borrelia species caused it, and how it was diagnosed and treated. The …

This study is looking at 100 women with polycystic ovary syndrome (PCOS) in Alsace, France. The goal is to better understand the different types of PCOS and why diagnosis is often delayed. Researchers will measure things like obesity rates and insulin resistance. No new treatment…

This study looks at how different types of platelets change in adults who need ECMO (a machine that helps the heart and lungs). Researchers want to see if these changes can explain bleeding or clotting problems. The study will follow 75 patients in the ICU for one week after star…

This study looks at how often physical restraints are used properly in the emergency departments of Strasbourg University Hospital. Researchers will check if doctors and nurses follow official best practice guidelines from 2021. They will also study which patients are most at ris…

This study looks at whether a special MRI scoring system called O-RADS can accurately predict if an ovarian mass in girls under 16 is cancerous or not. Researchers will review the MRI results of 100 girls who had surgery for ovarian masses. The goal is to help surgeons choose the…

This study looks at whether a rectal swab can help predict which intensive care patients will get infections from hard-to-treat bacteria. Researchers will test 1,000 adults in the ICU and track who later develops an infection. The goal is to see if a negative swab reliably means …

This study surveys healthcare professionals in European dialysis centers to understand how they measure intraperitoneal pressure (belly pressure) in children with kidney failure who are on peritoneal dialysis. The goal is to learn about current practices and improve how dialysis …

This study looks at what helps or hinders creating care plans for vulnerable patients in palliative care who live in medicalized residential facilities. Researchers will interview staff and others to understand the organizational and human factors involved. About 100 adults in Al…

This study looks back at the medical records of 400 full-term newborns who had very low cord blood pH (a sign of severe oxygen shortage during birth). Researchers want to find specific heart rate patterns that show when a baby is struggling and needs help. The goal is to help doc…

This study collects information from 1,300 people with rare diseases to better understand mouth and tooth problems that often come with these conditions. Researchers will look at dental history, family patterns, and genes to improve how these problems are diagnosed and treated. T…

This study looks at how to better choose antibiotics for people who say they are allergic to beta-lactam drugs (like penicillin) before orthopedic surgery. Many people think they are allergic, but only a few actually are. Researchers will use a simple questionnaire called the PEN…