University Hospital, Strasbourg, France
Clinical trials sponsored by University Hospital, Strasbourg, France, explained in plain language.
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New hope for diabetic dialysis patients: study tests vildagliptin plus insulin
Disease control CompletedThis study looked at whether adding the drug vildagliptin to insulin can help control blood sugar in people with type 2 diabetes who are on dialysis. 70 adults on dialysis took part. The researchers used continuous glucose monitoring to track blood sugar levels over 12 weeks. The…
Phase: PHASE4 • Sponsor: University Hospital, Strasbourg, France • Aim: Disease control
Last updated Apr 29, 2026 02:40 UTC
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Which biologic works best when the first one fails for rheumatoid arthritis?
Disease control CompletedThis study looked at 300 people with rheumatoid arthritis whose first anti-TNF biologic stopped working. Researchers compared switching to a different anti-TNF versus trying a biologic with a different mechanism. The goal was to see which approach better controls disease activity…
Phase: PHASE4 • Sponsor: University Hospital, Strasbourg, France • Aim: Disease control
Last updated Apr 29, 2026 02:39 UTC
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Sandblasting teeth may keep braces retainers stuck longer
Disease control CompletedThis study looked at 88 people aged 11 and older who finished braces and got a permanent wire glued behind their lower front teeth to keep them straight. Researchers compared two ways of preparing the teeth before gluing: sandblasting the enamel versus the usual pumice polishing.…
Phase: NA • Sponsor: University Hospital, Strasbourg, France • Aim: Disease control
Last updated Apr 28, 2026 13:02 UTC
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Titanium jaw implant offers simpler reconstruction
Disease control CompletedThis study tested a new way to rebuild the front part of the jaw after surgery using a porous titanium implant. The goal was to avoid more complex bone grafts that often cause problems. Seven adults took part, and the implant was designed to be quick and easy to fix in place. The…
Phase: PHASE2 • Sponsor: University Hospital, Strasbourg, France • Aim: Disease control
Last updated Apr 28, 2026 13:01 UTC
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New test could spot lyme disease faster and more accurately
Diagnosis CompletedThis study tested a new diagnostic method (SRM-MS/MS) to detect Lyme disease from skin samples. It included 84 people with the early skin rash (erythema migrans). The new method was compared to standard tests (culture and PCR) to see which is more sensitive.
Phase: NA • Sponsor: University Hospital, Strasbourg, France • Aim: Diagnosis
Last updated Apr 28, 2026 13:02 UTC
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Could a Parkinson's psychosis drug also curb impulsive behaviors?
Symptom relief CompletedThis study tested whether pimavanserin, a drug already approved for hallucinations in Parkinson's, can reduce impulse control disorders like compulsive gambling or shopping. 117 adults with Parkinson's and moderate-to-severe impulse issues took the drug or a placebo for 8 weeks. …
Phase: PHASE2 • Sponsor: University Hospital, Strasbourg, France • Aim: Symptom relief
Last updated Apr 26, 2026 20:02 UTC
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Talking therapy shows promise for emotional struggles in autistic adults
Symptom relief CompletedThis study tested a 5-month program called Dialectical Behavior Therapy (DBT) for adults with autism who have trouble managing emotions and may harm themselves. 92 adults without intellectual disability took part. The goal was to see if DBT could reduce emotional distress and sel…
Phase: NA • Sponsor: University Hospital, Strasbourg, France • Aim: Symptom relief
Last updated Apr 26, 2026 20:02 UTC
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Blood clot patients monitored for better understanding of risks
Knowledge-focused CompletedThis study followed 300 people who had a blood clot in a vein (deep vein thrombosis or pulmonary embolism) to see how often clots come back or cause bleeding. Researchers wanted to find new risk factors and compare newer blood thinners to older ones. The study did not test a new …
Sponsor: University Hospital, Strasbourg, France • Aim: Knowledge-focused
Last updated Apr 29, 2026 02:54 UTC
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Heart valve mismatch: does it affect your exercise and heart health years later?
Knowledge-focused CompletedThis study looked at 77 younger patients (under 60) who had a mechanical aortic valve replacement to see if a mismatch between the valve size and their heart affects their exercise ability and heart recovery over the long term. Researchers measured oxygen use during exercise and …
Phase: NA • Sponsor: University Hospital, Strasbourg, France • Aim: Knowledge-focused
Last updated Apr 29, 2026 02:54 UTC
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New prostate biopsy technique shows promise for better accuracy and comfort
Knowledge-focused CompletedThis study looked at a newer way to take prostate tissue samples using MRI guidance through the perineum (the area between the scrotum and anus). The goal was to see if this method causes fewer complications and is more comfortable than the standard biopsy through the rectum. The…
Phase: PHASE4 • Sponsor: University Hospital, Strasbourg, France • Aim: Knowledge-focused
Last updated Apr 29, 2026 02:54 UTC
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Camera study reveals memory glitches in schizophrenia
Knowledge-focused CompletedThis study looked at how people with schizophrenia organize memories of everyday events. Participants took a 1-hour walk in the city while wearing an automatic camera around their neck. Later, they were shown pictures from the walk and asked to put them in the correct order and i…
Phase: NA • Sponsor: University Hospital, Strasbourg, France • Aim: Knowledge-focused
Last updated Apr 29, 2026 02:53 UTC
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Healthy nerve data could sharpen neuropathy diagnosis
Knowledge-focused CompletedThis study aims to establish normal values for nerve fiber density in the skin of healthy adults. By analyzing skin biopsies from 300 participants aged 20 to 80, researchers hope to improve the accuracy of diagnosing small fiber neuropathy. The study does not involve any treatmen…
Phase: NA • Sponsor: University Hospital, Strasbourg, France • Aim: Knowledge-focused
Last updated Apr 29, 2026 02:53 UTC
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Smartphone app aims to improve Post-Surgery drug management
Knowledge-focused CompletedThis study tested a smartphone app designed to help patients manage their medications after surgery. The app gave recommendations on which drugs to take and when. Researchers compared the app's advice to recommendations from a nurse to see if they matched. The study involved 37 a…
Phase: NA • Sponsor: University Hospital, Strasbourg, France • Aim: Knowledge-focused
Last updated Apr 29, 2026 02:52 UTC
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500 patients studied to unlock secrets of mesh infections
Knowledge-focused CompletedThis study reviewed the medical records of 500 adults who had hernia repair surgery with a mesh implant. The goal was to learn more about infections that can happen after this surgery, including what germs cause them and what factors make them more likely. By understanding these …
Sponsor: University Hospital, Strasbourg, France • Aim: Knowledge-focused
Last updated Apr 29, 2026 02:52 UTC
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Spine surgery study: does body position change how lungs react to breathing help?
Knowledge-focused CompletedThis study looked at 30 adults having major spine surgery to see how a breathing technique called alveolar recruitment maneuver (ARM) affects the lungs and heart when done in different body positions. ARMs help keep lungs open during surgery. The researchers compared doing ARM wh…
Sponsor: University Hospital, Strasbourg, France • Aim: Knowledge-focused
Last updated Apr 28, 2026 13:02 UTC
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Emergency room shoulder care under review
Knowledge-focused CompletedThis study looked at how doctors treat shoulder dislocations in the emergency room at a French hospital. Researchers reviewed past cases to find ways to reduce pain during treatment and create a standard care plan. The goal is to make care more consistent and less painful for pat…
Sponsor: University Hospital, Strasbourg, France • Aim: Knowledge-focused
Last updated Apr 26, 2026 20:01 UTC
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What makes us feel in control? scientists investigate in mental illness
Knowledge-focused CompletedThis study looked at how the brain creates the feeling of being in control of our own actions. Researchers compared healthy volunteers with people who have schizophrenia or bipolar disorder, especially those who feel their actions are controlled by an outside force. By studying s…
Phase: NA • Sponsor: University Hospital, Strasbourg, France • Aim: Knowledge-focused
Last updated Apr 26, 2026 20:01 UTC
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Can moderate exercise change how your body handles dietary fat?
Knowledge-focused CompletedThis study looked at how moderate physical activity influences the way the body processes different types of dietary fats in men with obesity. Twelve men aged 18-55 with a family history of obesity and a sedentary lifestyle participated. Researchers measured fat oxidation and gen…
Phase: NA • Sponsor: University Hospital, Strasbourg, France • Aim: Knowledge-focused
Last updated Apr 26, 2026 20:00 UTC