Scientists hunt for hidden genes in rare immune disorder

NCT ID NCT03427593

First seen Nov 01, 2025 · Last updated Jun 11, 2026 · Updated 33 times

Summary

This study looked at 27 adults with a severe immune system problem called Common Variable Immune Deficiency (CVID), who also had low white blood cells (neutropenia) and swollen lymph nodes (lymphoproliferation). The goal was to find gene changes that might cause these severe symptoms. Researchers used advanced gene sequencing to search for known and new mutations, and to understand the biological pathways involved.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Service d'Immunologie Clinique et VIH - Hôpital Civil

    Strasbourg, 67091, France

Conditions

Explore the condition pages connected to this study.