Flushing technique may boost egg retrieval in women with low ovarian reserve

NCT ID NCT01329302

Completed Symptom relief Sponsor: University Hospital, Strasbourg, France Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether flushing follicles with a special needle during egg retrieval helps women who produce few eggs in IVF. 257 women with fewer than 5 mature follicles were randomly assigned to standard aspiration or aspiration plus flushing. The goal was to see if flushing increases the number of mature eggs collected and improves pregnancy rates.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Follicular flushing with double lumen needle
What this could lead to: If successful, this technique could help women with low ovarian response retrieve more eggs during IVF, potentially increasing their chances of pregnancy.
What could go wrong: This is a completed study with 257 participants, but the benefit may be small and not apply to all patients. Flushing adds time and cost to the procedure.

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Conditions

The condition(s) this trial relates to.

female infertility ovarian dysfunction

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

INFERTILITY, FEMALE OVARIAN INSUFFICIENCY

Contacts and locations

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Locations

Centre d'Assistance Médicale à la Procréation, CMCO-SIHCUS

Schiltigheim, Schiltigheim, 67300, France

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