INFERTILITY, FEMALE

This study tests a simpler, lower-cost version of IVF called CAPA in-vitro maturation (IVM) for women with infertility or those needing to preserve their eggs (e.g., before cancer treatment). Unlike standard IVF, it uses less medication and has fewer health risks. The study will …

This study tests a device that uses ultrasound guidance to ablate (destroy) a small part of the ovary in women with infertility due to polycystic ovary syndrome (PCOS). The goal is to help them ovulate and become pregnant without needing long-term medication. About 195 women aged…

This study compares two ways to prepare the womb for a frozen embryo transfer: a modified natural cycle with progesterone and standard hormone therapy. The goal is to see which method leads to more live births and fewer pregnancy complications. About 336 women aged 21 to 44 with …

This study tests whether taking Clomid for a longer time (instead of the usual 5 days) helps women with low egg reserve produce more mature eggs during IVF. The longer protocol aims to increase egg numbers while reducing the need for expensive injections. About 120 women will be …

This study tests whether tadalafil, a drug that improves blood flow, can help women with unexplained infertility have better pregnancy outcomes during IVF. About 100 women with good-quality frozen embryos will take tadalafil to see if it thickens the uterine lining and increases …

This study tests whether a mindset management program called Organic Conceptions can lower stress levels in women dealing with infertility. About 66 women who are new patients at a fertility clinic will take part. Half will complete the program and all will fill out surveys to me…

This study tests whether taking Gushen Antai pills during IVF can increase the chance of an ongoing pregnancy (a heartbeat past 12 weeks). About 800 women with normal ovarian function will receive either the herbal pill or a placebo. The goal is to see if this traditional Chinese…

This study tests whether a daily 15-minute mindfulness app can lower anxiety and improve quality of life in 150 women undergoing their first IVF treatment. Participants either use the app or receive standard care. The goal is to see if the app helps with stress, depression, and p…

This study compares a long-acting hormone injection (corifollitropin alfa) to daily hormone shots in 318 egg donors aged 18–35. Both groups also take a pill (medroxyprogesterone acetate) to prevent early ovulation. The goal is to see if the single-shot approach yields a similar n…

This study looks at whether giving a GnRH agonist hormone injection before a frozen embryo transfer can help women with endometriosis or adenomyosis get pregnant. About 180 women aged 18 to 36 will be randomly assigned to receive either the hormone plus standard estrogen/progesti…

This study tests whether taking a low dose of the hormone hCG for eight weeks before IVF can help women with low ovarian reserve produce more eggs. About 80 women aged 18-40 will be randomly assigned to receive either hCG or a placebo before their second IVF cycle. The main goal …

This study looks at whether the level of a hormone called AMH in the fluid around a woman's eggs can help predict if an embryo is healthy (has the right number of chromosomes). Researchers will collect fluid from the first egg of each ovary during IVF in about 300 women aged 18-4…

This study looks at immune cells in the womb lining and blood of women with unexplained infertility or recurrent miscarriage, compared to fertile women. Researchers want to understand if differences in these cells affect the womb's ability to accept an embryo. The goal is to lear…

This study examines how different ovarian stimulation protocols affect blood clotting and clot breakdown in infertile women. Researchers will compare various stimulation methods to see how they influence thrombin formation and fibrinolysis. The study includes 300 women diagnosed …

This study looks at whether measuring telomeres (a marker of biological aging) can help find the root cause of infertility in women who have not gotten pregnant despite standard treatments like IVF. Fifteen women aged 25 to 42 will receive a personalized plan combining traditiona…

This study looks at how blood sugar levels change in women receiving fertility treatments like IVF. Researchers will use a continuous glucose monitor to track sugar patterns and see if those patterns are linked to pregnancy success. About 100 women aged 18 to 40 will take part.

This study looks at how women's feelings about artificial intelligence (AI) relate to their anxiety and quality of life while going through infertility treatment. About 191 women aged 18-45 who are currently receiving treatment will fill out surveys. The goal is to understand if …

This study offers girls facing cancer treatments or other health issues that could harm their fertility the chance to freeze ovarian tissue. The goal is to see how many later use that tissue to have children. Researchers will track trends over time to understand the impact of thi…

This study aims to better understand cervical mucus and find biological markers that could help diagnose or predict reproductive problems. Researchers will compare healthy women with those who have unexplained infertility by taking mucus samples and tracking their menstrual cycle…

This study looks at how physical activity, fitness, and mental health impact pregnancy rates in women receiving fertility treatments like IVF or IUI. Researchers will track 115 women's exercise habits, stress levels, and heart health to see if these factors are linked to better o…

This study looks at two ways to fertilize eggs in a lab – ICSI (injecting a single sperm into an egg) and conventional IVF (mixing eggs with sperm in a dish) – when using frozen donor sperm. About 95 women without male fertility problems will have their eggs split into two groups…

This study looks at whether exposure to chlordecone, a pesticide still present in the environment, is linked to lower fertility in women. Researchers will measure levels of the chemical in the blood of 634 women seeking fertility treatment in Guadeloupe and compare it to their ov…