One shot instead of many: new egg donor study aims to ease treatment burden

NCT ID NCT06193135

Recruiting now Disease control Sponsor: Instituto Valenciano de Infertilidad, IVI VALENCIA Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study compares a single injection of corifollitropin alfa (Elonva) to daily shots of follitropin beta (Puregon) for ovarian stimulation in egg donors. Both groups also take medroxyprogesterone acetate to prevent early ovulation. The goal is to see if the simpler one-shot approach yields a similar number of mature eggs while reducing the physical and emotional strain of daily injections. The trial enrolls 318 healthy women aged 18–35 who are egg donors.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: corifollitropin alfa (Elonva) and follitropin beta (Puregon)
What this could lead to: If it works, this could simplify ovarian stimulation for egg donors, reducing the number of injections and easing the physical and emotional burden of treatment.
What could go wrong: This is a mid-sized trial (318 participants) comparing two established drugs, so the main risk is that the single-shot approach may not produce as many usable eggs as daily injections, or may cause similar side effects like bloating or ovarian hyperstimulation.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for INFERTILITY, FEMALE are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

female infertility infertility disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

INFERTILITY, FEMALE REPRODUCTIVE STERILITY

Contacts and locations

Locations

IVI Valencia
RECRUITING

Valencia, Valencia, 46015, Spain
Ivi Valencia
RECRUITING

Valencia, Valencia, 46015, Spain

More trials for these conditions

Other studies related to the condition(s) this trial covers.