One shot instead of many: new egg donor study aims to ease treatment burden
NCT ID NCT06193135
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study compares a single injection of corifollitropin alfa (Elonva) to daily shots of follitropin beta (Puregon) for ovarian stimulation in egg donors. Both groups also take medroxyprogesterone acetate to prevent early ovulation. The goal is to see if the simpler one-shot approach yields a similar number of mature eggs while reducing the physical and emotional strain of daily injections. The trial enrolls 318 healthy women aged 18–35 who are egg donors.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
corifollitropin alfa (Elonva) and follitropin beta (Puregon)
What this could lead to
If it works, this could simplify ovarian stimulation for egg donors, reducing the number of injections and easing the physical and emotional burden of treatment.
What could go wrong
This is a mid-sized trial (318 participants) comparing two established drugs, so the main risk is that the single-shot approach may not produce as many usable eggs as daily injections, or may cause similar side effects like bloating or ovarian hyperstimulation.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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IVI Valencia
RECRUITINGValencia, Valencia, 46015, Spain
Contact
Contact Email: •••••@•••••
Contact
Contact Email: •••••@•••••
Contact
-
Ivi Valencia
RECRUITINGValencia, Valencia, 46015, Spain
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••