IVF Needle-Free? oral pill tested as injection alternative
NCT ID NCT07732348
First seen Jul 28, 2026 · Last updated Aug 04, 2026 · Updated 3 times
Summary
This trial tests whether an oral medication called linzagolix can replace daily injections used to prevent premature ovulation during in vitro fertilization (IVF). The study compares the number of mature eggs retrieved in women taking the pill versus those receiving standard injectable drugs. A separate group using a different hormonal protocol is also included for comparison. The goal is to see if the oral option works just as well while being easier to take.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- an oral GnRH antagonist called linzagolix, compared with injectable GnRH antagonists (ganirelix or cetrorelix)
- What this could lead to
- If it works, this could offer women undergoing IVF a simpler, needle-free option to prevent premature ovulation, potentially reducing stress and discomfort.
- What could go wrong
- This is an early-phase trial with a small number of participants, so results may not be conclusive. Linzagolix is not yet approved for this use, and its effectiveness and safety in IVF are unproven.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for INFERTILITY, FEMALE are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Obesity may blunt the Brain's ovulation signal, study hints
- Could a fibroid drug help women with adenomyosis finally achieve a live birth?
- Could a blood injection revive aging ovaries?
- Could a shot of your own blood help your ovaries produce more eggs?
- Blood plasma injection aims to wake up dormant ovaries in menopause
- Could a shot of your own blood boost fertility?