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One shot instead of many: a simpler path to IVF egg retrieval?

NCT ID NCT06635538

Knowledge-focused Sponsor: Fundación Santiago Dexeus Font Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 08, 2026 · Last updated Sep 09, 2026 · Updated 1 time

Summary

This pilot study tests a streamlined ovarian stimulation protocol for women undergoing fertility treatment. Participants receive a single injection of corifollitropin alfa plus daily oral clomiphene citrate, instead of the usual multiple daily injections. Researchers will measure hormone levels and egg retrieval outcomes to see if this simpler approach works as well as standard protocols.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
A single injection of corifollitropin alfa plus daily oral clomiphene citrate
What this could lead to
If this works, it could simplify ovarian stimulation for IVF, reducing the number of injections women need while maintaining good egg retrieval outcomes.
What could go wrong
This is a small pilot study with only 20 participants, so results may not apply broadly. The approach might not produce enough eggs or could cause hormone imbalances.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

20 people

The number who actually took part.

Started

Oct 2024

Finished

Nov 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 40 years

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: Age \<= 40 AMH (Anti-Mullerian Hormone) 1.2-3.5 ng/ml or AFC 7-20 No family history of hereditary or chromosomal diseases Body mass index (BMI) 18 to 30 kg/m2

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Conditions

The condition(s) this trial relates to.

female infertility

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Infertility, female

Contacts and locations

Locations

  • Departamento de Ginecología Obstetricia y Reproducción. Hospital Universitari Dexeus

    Barcelona, 08037, Spain

  • Dexeus Mujer Sabadell

    Sabadell, Barcelona, 08203, Spain

  • Dexeus Mujer Sant Cugat

    Sant Cugat del Vallès, Barcelona, 08195, Spain

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