Could a Parkinson's psychosis drug also curb impulsive behaviors?

NCT ID NCT03947216

First seen Mar 22, 2026 · Last updated Apr 25, 2026 · Updated 3 times

Summary

This study tested whether pimavanserin, a drug already approved for hallucinations in Parkinson's, can reduce impulse control disorders like compulsive gambling or shopping. 117 adults with Parkinson's and moderate-to-severe impulse issues took the drug or a placebo for 8 weeks. The goal was to see if symptoms improved without worsening movement problems.

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Contacts and locations

Locations

  • Centre d'Inverstigation Clinique, CHU de Poitiers

    Poitiers, 86021, France

  • SERVICE DE NEUROLOGIE C, Unité mouvement anormaux/Centre expert Parkinson, CHU de Lyon, Hopital neurologique Pierre Wertheimer

    Bron, 69677, France

  • SERVICE DE NEUROLOGIE Centre Expert Parkinson Hopital de la Pitié-Salpêtrière

    Paris, 75651, France

  • SERVICE DE NEUROLOGIE Unité de Mouvements Anormaux/Centre expert Parkinson, CHU de Strasbourg, Hopital de Hautepierre

    Strasbourg, 67098, France

  • SERVICE DE NEUROLOGIE, CHU de REIMS

    Reims, 51100, France

  • SERVICE DE NEUROLOGIE, Unité Mouvement Anormaux/Centre expert Parkinson, CHU de Lille, Hopital Roger Salengro

    Lille, 59037, France

  • SERVICE DE NEUROLOGIE, Unité Mouvement Anormaux/Centre expert Parkinson, Hopital de la Timone

    Marseille, 13385, France

  • SERVICE DE NEUROLOGIE, Unité Mouvements Anormaux/Centre expert Parkinson CHU Clermont-Ferrand, Hopital Gabriel Montpied

    Clermont-Ferrand, 63003, France

  • SERVICE DE NEUROLOGIE, Unité Mouvements Anormaux/Centre expert Parkinson, CHU de Grenoble Alpes

    Grenoble, 38043, France

  • SERVICE DE NEUROLOGIE, Unité Mouvements Anormaux/Centre expert Parkinson, CHU de Limoges

    Limoges, 87042, France

  • SERVICE DE NEUROLOGIE, Unité Mouvements Anormaux/Centre expert Parkinson, CHU de Rennes, Hopital Pontchaillou

    Rennes, 35033, France

  • SERVICE DE NEUROLOGIE, Unité Mouvements Anormaux/Centre expert Parkinson, CHU de Rouen, Hopital Charles Nicolle

    Rouen, 76031, France

  • SERVICE DE NEUROLOGIE, Unité Mouvements Anormaux/Centre expert Parkinson, CIC, CHU de Nantes, Hopital Laennec

    Nantes, 44093, France

  • SERVICE DE NEUROLOGIE, Unité Mouvements Anormaux/Centre expert Parkinson, CIC, CHU de Toulouse, Hopital Pierre-Paul Riquet

    Toulouse, 31059, France

  • SERVICE DE NEUROLOGIE, Unité Mouvements Anormaux/Centre expert Parkinson, Hopital Henri Mondor

    Créteil, 94010, France

  • Service de Neurologie and CIC -CHU Besançon

    Besançon, France

Conditions

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