Freezing out tumors: new hope for rare desmoid disease
NCT ID NCT02476305
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested a freezing technique called cryoablation on 50 adults with desmoid tumors that had grown despite medical treatment. The goal was to stop tumor growth and ease symptoms without surgery. Researchers used MRI to guide the freezing and check results one year later.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- cryoablation (freezing therapy using cryoprobes)
- What this could lead to
- If successful, cryoablation could provide a non-surgical way to control desmoid tumors, reduce pain, and improve quality of life for patients who have not responded to other treatments.
- What could go wrong
- This is a small, early-phase study (50 participants) with no control group. The procedure may not work for all tumor locations, and there is a risk of incomplete destruction or recurrence.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Service d'Imagerie Interventionnelle
Strasbourg, Alsace, 67091, France
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