Sound waves vs. tumors: new ultrasound treatment tested for sarcoma

NCT ID NCT05111964

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This pilot study is testing whether high-intensity focused ultrasound (HIFU) can safely destroy soft tissue sarcoma and small desmoid tumors without surgery. About 10-16 adults with these tumors will receive a single outpatient treatment using a CE-approved device. The goal is to see if the procedure is feasible and safe, and to gather early data on how well it works, including tumor destruction and immune response.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

High intensity focused ultrasound (HIFU) device

What this could lead to

If successful, this could offer a non-invasive, outpatient treatment option for soft tissue sarcoma and desmoid tumors, potentially reducing the need for surgery or radiation.

What could go wrong

This is a very small pilot study (10-16 patients) focused on safety and feasibility, not effectiveness. The technology is still experimental for these tumors, and risks include incomplete tumor destruction or complications requiring surgery.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

desmoid tumor sarcoma soft tissue sarcoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Churchill Hospital

    RECRUITING

    Oxford, Oxfordshire, United Kingdom

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    Contact Email: •••••@•••••

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