Oxford University Hospitals Nhs Trust

This trial tests whether using a suction catheter to remove large blood clots before placing a stent improves outcomes in people having a severe heart attack (STEMI). Participants must have a large clot visible on angiography. Half receive standard stent placement alone, and half…

This pilot study is testing whether high-intensity focused ultrasound (HIFU) can safely destroy soft tissue sarcoma and small desmoid tumors without surgery. About 10-16 adults with these tumors will receive a single outpatient treatment using a CE-approved device. The goal is to…

This study looks at whether a structured ultrasound program (OxGRIP) can help detect babies that are not growing well in the womb, which is a major risk factor for stillbirth. The program adds a routine scan at 36 weeks and extra scans for at-risk women. Researchers will compare …

This study tests whether injecting a patient's own blood into the lung lining (a pleural blood patch) can prevent air leaks after thermal ablation for lung cancer. About 106 adults scheduled for lung ablation will be randomly assigned to receive the blood patch or not. The main g…

This pilot study compares a nerve-freezing technique called cryoneurolysis to standard Botox injections for treating pain and stiffness caused by spasticity in people with brain or spinal cord injuries, multiple sclerosis, or stroke. Fifty adults will be randomly assigned to rece…

This study follows 2,000 people with monoclonal gammopathy of undetermined significance (MGUS), a condition that can precede multiple myeloma, a rare blood cancer. The goal is to measure how often MGUS progresses to myeloma and to understand current monitoring practices. Particip…

This study looks at why people with hemophilia (a bleeding disorder) are less likely to die from heart disease. Researchers will use a new, detailed CT scanner to compare heart artery health in 80 men aged 45+ with hemophilia to similar men without it. The goal is to understand h…