Can tracking a precancerous condition slash myeloma diagnosis delays?

NCT ID NCT05539079

First seen Aug 05, 2026 · Last updated Aug 06, 2026 · Updated 1 time

Summary

This study follows 2,000 people with monoclonal gammopathy of undetermined significance (MGUS), a condition that can precede multiple myeloma, a rare blood cancer. The goal is to measure how often MGUS progresses to myeloma and to understand current monitoring practices. Participants will complete annual questionnaires for up to five years, and some will provide blood samples. The findings could lead to better screening and earlier diagnosis of myeloma.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this study could improve early detection of myeloma by clarifying how MGUS progresses and how it should be monitored, potentially reducing diagnostic delays.
What could go wrong
This is an observational study, so it won't test a treatment. Results depend on long-term follow-up and may not change clinical practice immediately.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Secure Study

    RECRUITING

    Oxford, Oxfordshire, OX3 7LE, United Kingdom

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