Fasting at night may cut cancer risk in people with blood disorder precursors
NCT ID NCT05565638
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested whether fasting for at least 14 hours each night could help overweight people with early blood cancer conditions (MGUS, smoldering myeloma) lose weight and possibly lower their cancer risk. Twenty-three participants were randomly assigned to either the fasting program or a healthy lifestyle education group for 4 months. The main goal was to see changes in body composition, with secondary measures of blood markers related to cancer progression.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- prolonged nightly fasting (behavioral intervention)
- What this could lead to
- If this works, it could point toward a simple lifestyle change—extending the nightly fast—to help prevent blood cancer in people with early warning signs.
- What could go wrong
- This is a very small, early study (23 participants) testing weight loss, not cancer directly. The fasting intervention may be hard to stick with long-term, and any cancer benefit is uncertain.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Dana Farber Cancer Institute
Boston, Massachusetts, 02115, United States
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