TYPE 2 DIABETES MELLITUS

This large, late-stage study is testing whether injecting a person's own processed kidney cells back into their kidneys can slow or stop the progression of kidney disease caused by type 2 diabetes. About 685 participants will be randomly assigned to receive either the real cell i…

This early-stage study is testing a new drug called maridebart cafraglutide to see if it can help the body use insulin better and improve how the pancreas produces insulin in people with type 2 diabetes. The trial will enroll 70 adults who are already taking metformin. Participan…

This study is testing a new weekly injection called RO7795068 to see if it helps people with obesity or overweight and type 2 diabetes lose weight and better control their blood sugar. About 1,600 participants will receive either the active drug or a placebo (dummy injection) for…

This study is testing a new drug, RO7204239, to see if it can help the body use insulin more effectively in people with type 2 diabetes who are also overweight or have obesity. It will compare the drug against a placebo (a dummy treatment) in 30 participants over 24 weeks. Resear…

This study is testing whether a new automated insulin pump system called MiniMed NMX8 is safe for people with diabetes. The trial will include 400 children and adults with type 1 or type 2 diabetes who will use the pump for 90 days while researchers monitor their blood sugar leve…

This study is testing if a new continuous glucose monitoring (CGM) system helps adults with type 1 or insulin-dependent type 2 diabetes keep their blood sugar in a healthy range better than the standard finger-prick method. About 270 participants will be randomly assigned to use …

This study is testing whether a new combination of medicines called 'Madalena association' can help control blood sugar in adults with type 2 diabetes. It will involve about 270 people whose current two-drug treatment isn't working well enough. Researchers will compare the new tr…

This study is testing a new daily medicine called RO7795081 for people with type 2 diabetes. Over 30 weeks, researchers will compare it to a placebo (inactive pill) and an existing diabetes drug to see if it safely lowers long-term blood sugar levels and body weight. The goal is …

This study aims to understand how a new investigational drug for Type 2 diabetes, called LY3209590, is processed by the body in children and teenagers. It involves giving a single dose to about 22 young participants and tracking the drug levels in their blood over approximately 1…

This study is testing how accurate a new, painless glucose sensor is. The device, called the LabPatch, is a small patch placed on a finger to measure blood sugar without drawing blood. Researchers will compare its readings to standard finger-prick meters and a lab analyzer in 60 …

This study aims to see if simple strategies can encourage people with prediabetes or type 2 diabetes to buy more whole grains instead of refined grains when shopping for groceries online. Researchers will test two approaches: using marketing nudges (like highlighting whole grain …

This study is collecting information about how the drug finerenone is used in everyday medical practice for people with chronic kidney disease and type 2 diabetes. Researchers will analyze existing health records from 50,000 patients in Asia and the United States who are already …

This study observes adults with risk factors like high blood pressure or diabetes during their regular cardiology visits. Researchers will collect health data to see how structured management affects measures like blood pressure and cholesterol. The goal is to better understand h…

This study aims to understand why certain diabetes medications work better for some people than others. Researchers will look back at the medical records of 300 people with type 2 diabetes who took specific injectable medications for at least 6 months. They will check if differen…

This study is testing if a detailed ultrasound scan of the neck artery can spot early signs of heart disease in people with Type 2 diabetes. Researchers will compare scans from 80 people with diabetes to those without diabetes. The goal is to see if this scan is better than curre…

This early-stage study aims to understand how a new investigational drug, AZD6793, interacts with the common diabetes medication metformin. It will involve about 28 people with type 2 diabetes who are already taking metformin. The main goal is to see if AZD6793 changes how the bo…

This study aims to understand how the kidney-protecting drug finerenone is actually used by doctors and patients in South Korea. Researchers will observe and collect information from about 500 adults with chronic kidney disease and type 2 diabetes who are starting this already-ap…

This study aims to understand the connection between gut health and brain function in older adults with type 2 diabetes. Researchers will follow 136 participants for a year to see if the common diabetes medication metformin changes the mix of gut bacteria and, in turn, affects me…