Diabetes drug may protect the brain: canagliflozin tested for cognitive decline
NCT ID NCT07711171
First seen Jul 17, 2026 · Last updated Jul 17, 2026
Summary
This study investigates whether canagliflozin, a diabetes medication, can improve cognitive function in people with type 2 diabetes who also have mild cognitive impairment. The trial uses brain scans to measure changes in blood flow after insulin inhalation, along with standard cognitive tests. Participants take canagliflozin or another diabetes drug for six months to compare effects on brain health.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- canagliflozin
- What this could lead to
- If successful, this could point toward a treatment that protects brain health in people with type 2 diabetes and early memory problems.
- What could go wrong
- This is a small, early-phase study with only 60 participants, so results may not apply widely. The cognitive benefits are uncertain and may not be clinically significant.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Locations
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Fudan University affiliated Huadong Hospital
RECRUITINGShanghai, Shanghai Municipality, China
Contact
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