Automated blood test strategy could spot hidden liver disease in routine checkups
NCT ID NCT07658755
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
LiverSeek is a study testing an automated screening program for advanced liver fibrosis in people aged 50-75 with risk factors like diabetes or obesity. When a routine blood test is done, the lab system automatically calculates a fibrosis score and, if needed, orders additional tests without the doctor having to act. The goal is to see how many high-risk patients have liver scarring and whether this approach can catch it early.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- automated screening strategy using blood tests (FIB-4, ELF, MASEF) and nurse-led lifestyle intervention
- What this could lead to
- If successful, this could lead to a simple, automated way to catch liver fibrosis early in primary care, potentially preventing progression to severe liver disease.
- What could go wrong
- This is an observational screening study, not a treatment trial. It may not prove that early detection improves outcomes, and the lifestyle intervention sub-study is small.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Hospital General Universitario Gregorio Marañón
RECRUITINGMadrid, Madrid, 28007, Spain
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