TYPE 2 DIABETES MELLITUS

This study tests whether a three-month smartphone-supported walking program can improve daily step counts, psychological well-being, and body composition in adults with cardiovascular disease or type 2 diabetes. Participants use the Walk15 app to set personalized step goals and t…

This study tested whether adding mindful eating training to a low-carb diet education helps people with type 2 diabetes follow the diet better. About 125 adults were randomly assigned to get either diet education alone or diet education plus mindful eating sessions. The main goal…

This completed study tested whether resveratrol, a natural compound found in grapes and berries, can improve blood vessel health and blood sugar control in people with type 2 diabetes. 48 adults took either a resveratrol pill or a placebo daily for 12 weeks. Researchers measured …

This early-phase study tested whether a single infusion of donor stem cells could help repair damaged blood vessels in 26 adults with type 2 diabetes and symptomatic heart disease. Researchers measured blood vessel function and looked for signs of repair in the lab. The goal was …

This study looked at whether gastric bypass surgery or the best medical care is more effective for obese people with poorly controlled type 2 diabetes. Researchers tracked 66 participants to compare death rates, weight loss, blood sugar control, quality of life, and costs. The go…

This study tested whether applying a probiotic (Lactobacillus reuteri) directly into gum pockets, alongside standard deep cleaning, improves gum health in people with type 2 diabetes. Fourteen adults with moderate to severe gum disease and controlled diabetes took part. Each pers…

This study looked at how the diabetes drugs glyburide and metformin work in pregnant women with gestational diabetes. 177 women between 20 and 32 weeks pregnant took part. The goal was to find the right dose and understand how these drugs control blood sugar and improve insulin f…

This study tested whether GLP-1 receptor agonists, a type of diabetes drug, can improve heart function and reduce fat around the heart in 44 obese adults with type 2 diabetes. Participants received the drug BYETTA along with metformin. Researchers used MRI scans to measure heart …

This study tested a visual injection site map to help people with diabetes rotate where they inject insulin. The goal was to reduce lipohypertrophy—lumpy fatty tissue caused by repeated shots in the same spot—and improve blood sugar control. 170 adults on insulin for at least six…

This study tested a wearable insulin pump system (Omnipod M) in 40 adults aged 18-75 with type 2 diabetes. The goal was to see if the system helps keep blood sugar in a safe range and reduces dangerous highs and lows. Participants used the system for 6 weeks, and researchers meas…

This study looked at whether keeping blood sugar very low (under 130 mg/dL) is better than standard control (130-180 mg/dL) for non-critically ill patients with diabetes in the hospital. Researchers tracked 600 patients for complications like death, severe low blood sugar, infect…

This study looked at whether testosterone therapy can improve bone health in men who have both type 2 diabetes and low testosterone. About 92 male veterans aged 35 to 70 took part. Researchers measured bone strength using special scans and blood tests over 12 months to see if tes…

This study tested whether eating more protein (1.5 grams per kilogram of body weight daily, instead of the usual 0.8 grams) could help older adults with type 2 diabetes prevent muscle loss and improve muscle function. Twenty-five participants followed either a high-protein or sta…

This study tested whether empagliflozin, a diabetes medication, lowers blood pressure more than other diabetes pills in adults with type 2 diabetes and high blood pressure. 300 participants took either empagliflozin or another diabetes drug for 12 weeks. Researchers measured bloo…

This completed study tested different combinations of diabetes drugs (glimepiride, empagliflozin, or sitagliptin) taken with metformin in 172 adults newly diagnosed with type 2 diabetes. Participants were split into four groups and took their assigned pills once daily for 90 days…

This study tested a program designed to help women with type 2 diabetes become more physically active. 86 women aged 30-65 took part. The program included a video, a pamphlet, and regular check-ins to encourage exercise. The goal was to see if this approach could increase daily a…

This study screened 316 people with type 2 diabetes who were at high risk for heart disease. Researchers tested whether adding the drug liraglutide to standard care could reduce new heart problems like heart attacks, strokes, and hospitalizations. The goal was to see if this appr…

This Phase 3 trial tested a new weekly injection called TG103, combined with the common diabetes pill metformin, in 632 adults with type 2 diabetes. The goal was to see if TG103 could lower blood sugar better than an existing weekly shot (dulaglutide) over 28 weeks. Participants …

This study tested a new weekly injection called TG103 in 465 adults with type 2 diabetes whose blood sugar was not well controlled by diet and exercise alone. Participants received either a low dose, a higher dose, or a placebo for several weeks. The main goal was to see if TG103…

This study looked at how a new medicine, LY3209590, is processed in the bodies of 15 children with type 2 diabetes. Each child received one dose, and researchers measured the drug levels in their blood over time. The goal was to understand how the drug is absorbed and removed, no…

This study tested a personalized dietary program for 30 adults with type 2 diabetes. The program was designed to help participants better manage their blood sugar and potentially achieve remission. Researchers measured changes in HbA1c and other health markers to see if the diet …

This study tested an experimental cell therapy called REACT (rilparencel) in 53 adults with type 1 or 2 diabetes and chronic kidney disease. The therapy involves injecting a person's own kidney cells into their kidneys to see if it can slow the loss of kidney function. The goal i…

This completed observational study looked at over 2,000 adults with type 2 diabetes who were already taking metformin plus another diabetes drug. Researchers wanted to see if adding a new combination pill called Zemidapa (which contains two diabetes medicines) could improve blood…

This study tested whether the drug dapagliflozin (Forxiga) works better than standard treatments for people with type 2 diabetes whose blood sugar is not well controlled on metformin alone. Over 600 adults took either dapagliflozin plus metformin or usual care (like sulfonylureas…

This study tested whether a once-weekly injection of exenatide (a diabetes drug) can protect the heart and kidneys in 57 adults with type 2 diabetes and mild kidney problems. Participants received either exenatide or a placebo for 38 weeks. Researchers measured blood and urine ma…

This study tested a 12-week intensive exercise program (aerobic and resistance training) in 58 adults aged 40-85 with type 2 diabetes and mild cognitive issues. The goal was to see if exercise could improve thinking, blood sugar, inflammation, and physical function. Results may h…

This pilot study tested whether using smart insulin pens together with continuous glucose monitors (CGMs) can improve blood sugar control in adults with type 2 diabetes. Thirty participants used these devices to track their glucose levels and insulin doses. The goal was to see if…

This study tested a new daily injection called CT-868 in 103 overweight or obese adults with type 2 diabetes. Participants received either the drug or a placebo for 26 weeks. The main goal was to see if CT-868 could lower blood sugar levels (HbA1c) and help with weight loss.

This completed phase 4 trial compared two common diabetes drugs, dapagliflozin and empagliflozin, added to metformin in 108 adults with type 2 diabetes and nonalcoholic fatty liver disease (NAFLD). Participants took one of the two drugs daily for six months. Researchers used live…

This study tested whether a simplified approach to starting automated insulin delivery works safely in adults with type 2 diabetes. 56 participants used the Omnipod M System with a continuous glucose monitor, starting with either a lower or higher insulin dose. The goal was to se…

This study tested a new medicine called CagriSema, which combines two drugs (cagrilintide and semaglutide) in one weekly injection, for weight loss in 1200 adults who are overweight or obese and have type 2 diabetes. Participants received either CagriSema or a placebo for about 1…

This study tested whether a new map for insulin injection sites (either digital or paper) could reduce skin lumps caused by insulin. 170 adults with diabetes who had been using insulin for at least six months took part. The map helped people rotate injection spots, aiming to impr…

This Phase 3 trial tested whether a new injectable drug, HR17031, works better than standard insulin glargine for controlling blood sugar in Chinese adults with type 2 diabetes. The study included 401 people whose diabetes was not well controlled with oral medications. Researcher…

This Phase 3 trial tested CagriSema, a once-weekly injection combining two medicines (cagrilintide and semaglutide), in 2734 adults with type 2 diabetes. The goal was to see if the combo lowers blood sugar and body weight better than either drug alone or a placebo. All participan…

This phase 2 study tested three different doses of a new injectable drug called maridebart cafraglutide (AMG 133) against a placebo in 592 adults who were overweight or obese, some with type 2 diabetes. The main goal was to see how much weight participants lost over 52 weeks. The…

This early-phase trial tested the safety and tolerability of a new drug called ZT002 in 32 healthy volunteers. Participants received either a single or multiple doses of ZT002 or a placebo by injection. The study aims to see if the drug is safe enough to move into larger trials f…

This study looked at whether weight-loss surgery (vertical sleeve gastrectomy) can improve kidney, heart, and pancreas function in teens aged 12-21 with type 2 diabetes and obesity. Researchers measured blood flow to the kidneys, kidney filtering ability, and insulin production b…

This early-stage study tested an experimental diabetes drug called TA-7284 in 24 people with type 2 diabetes, some with normal kidneys and some with moderate kidney impairment. Researchers measured how the drug moves through the body, how it affects blood sugar, and whether it is…

This study tested a new weekly injection called CagriSema, which combines two drugs (cagrilintide and semaglutide), to help Chinese adults with obesity or overweight lose weight. About 300 participants received either CagriSema, semaglutide alone, or a placebo for around one year…

This Phase 2 trial tested an experimental oral drug called TA-7284 in 383 adults with type 2 diabetes. The drug works by helping the kidneys remove extra sugar through urine. Researchers compared four different doses of TA-7284 against a placebo to see how well it lowers blood su…

This study tested whether adding canagliflozin, a diabetes pill, to insulin therapy helps people with type 2 diabetes control their blood sugar better. 146 adults took either canagliflozin or a placebo for 16 weeks while continuing their insulin. Researchers measured changes in b…

This study looked at whether adding canagliflozin to an existing GLP-1 medication is safe and helpful for people with type 2 diabetes. 71 adults took the combination for 52 weeks. Researchers tracked side effects, blood sugar levels, weight, and blood pressure. The goal was to se…

This study tested an experimental drug called TA-7284 in 272 adults with type 2 diabetes. Participants took either a low dose, high dose, or a placebo pill daily for 24 weeks. The goal was to see if the drug safely lowers blood sugar levels (measured by A1C) compared to placebo.

This study tested an experimental drug called TA-7284 in 61 adults with type 2 diabetes. Participants took different doses (25 to 400 mg) or a placebo once daily for 15 days. The main goal was to check safety and how the drug moves through the body, with a secondary look at its e…

This study looked at the long-term safety and effectiveness of adding canagliflozin to insulin therapy in adults with type 2 diabetes. A total of 139 people who had completed a previous 16-week study took part. Researchers tracked side effects, blood sugar control, and weight cha…

This study tested a new medication, TA-7284, in 1,299 adults with type 2 diabetes over 52 weeks. The goal was to see if the drug is safe and helps control blood sugar when used alone or with other diabetes medicines. Results focused on side effects, blood sugar levels, and weight…

This study tested whether adding teneligliptin to canagliflozin helps Japanese adults with type 2 diabetes who still have high blood sugar despite taking canagliflozin alone. Over 24 weeks, 154 participants took both drugs once daily. The main goal was to see if the combination l…

This study tested a drug called teneligliptin in 254 Chinese adults with type 2 diabetes. Half received the drug and half received a placebo for 24 weeks. The main goal was to see if teneligliptin lowers blood sugar levels (HbA1c) better than a placebo. Researchers also checked f…

This study tested four different doses of a new drug called MP-513 in 448 adults with type 2 diabetes who were already taking metformin. The goal was to see which dose works best and is safe for lowering blood sugar over 24 weeks, with an extension up to 52 weeks. Participants to…

This study tested whether adding canagliflozin to the existing diabetes drug teneligliptin helps Japanese adults with type 2 diabetes who still have high blood sugar. Over 24 weeks, researchers measured changes in HbA1c (a key blood sugar marker), fasting glucose, and body weight…

This phase 3 study tested whether adding teneligliptin to metformin helps Chinese adults with type 2 diabetes control their blood sugar better than metformin alone. 247 participants took either teneligliptin or a placebo for 24 weeks. The main goal was to see if HbA1c (a measure …

This study tested a once-daily combination of two diabetes drugs (Teneligliptin and Canagliflozin) in 153 Japanese adults with type 2 diabetes whose blood sugar was not well controlled on Teneligliptin alone. Participants took the combo pill for 52 weeks to see if it was safe and…

This study tested whether adding teneligliptin to standard sulfonylurea therapy improves blood sugar control in 194 Japanese adults with type 2 diabetes. Participants received either teneligliptin or a placebo for 12 weeks, followed by an open-label extension for up to 52 weeks. …

This study tested a new diabetes drug called teneligliptin (MP-513) combined with pioglitazone in 204 Japanese adults with type 2 diabetes. Participants took the combination for 12 weeks, then continued for up to a year. The main goal was to see if it lowered blood sugar levels (…

This study tested the long-term safety and blood sugar control of the drug MP-513 (Teneligliptin) in 240 Japanese adults with type 2 diabetes. Some participants took MP-513 alone, while others took it together with another diabetes medicine called glimepiride. The study lasted 52…

This study tested the long-term safety of MP-513 (Teneligliptin) in 462 Japanese adults with type 2 diabetes. Participants took the drug alone or with other oral diabetes medicines for 52 weeks. The main goal was to track side effects, and researchers also measured blood sugar co…

This study tested a new diabetes medicine called MP-513 (Teneligliptin) in 203 Japanese adults with type 2 diabetes. The goal was to see if the drug safely lowers blood sugar levels over 12 weeks. Participants took either the drug or a placebo pill, and researchers measured chang…

This study tested whether adding the diabetes pill teneligliptin to insulin helps people with type 2 diabetes control their blood sugar better. 148 Japanese adults who were already on a stable insulin dose took either teneligliptin or a placebo for 16 weeks, with an extension up …

This study tested a new drug called MP-513 in 99 Japanese adults with type 2 diabetes. The goal was to see how well it controls blood sugar levels over 4 weeks. Participants took the drug and had their blood sugar measured after meals and throughout the day.

This study tested whether caring for a live turtle or watching turtle videos could help adults with type 2 diabetes improve their blood sugar control and feel more confident about taking their diabetes medication. Fifty-one participants were split into three groups: live turtle c…

This study tested two ways of taking insulin in people with type 2 diabetes. One group took a mix of long- and fast-acting insulin twice a day. The other group took the mix once a day plus extra fast-acting insulin at meals. After 16 weeks, researchers compared blood sugar contro…

This study tested an AI system called X Life that gives personalized diet and exercise tips to people with prediabetes or type 2 diabetes. Twenty participants used the system for 7 days via AR glasses or a smartphone. The goal was to see if people found it easy and helpful, not t…

This study tested whether a weekly injection of semaglutide (2.4 mg) can improve heart failure symptoms and reduce body weight in 617 people with obesity-related heart failure with preserved ejection fraction and type 2 diabetes. Participants received either semaglutide or a plac…

This Phase 3 trial tested whether HTD1801 (berberine ursodeoxycholate) can help people with type 2 diabetes who aren't well controlled on metformin alone. Over 500 participants received either the drug or a placebo for 24 weeks. The main goal was to see if the drug lowered blood …

This completed Phase 4 trial tested two different drug combinations in 200 adults with type 2 diabetes to see which helped reduce body weight more. Participants took either empagliflozin plus linagliptin or empagliflozin plus metformin for 12 weeks. Researchers measured changes i…

This study tested whether taking bitter melon, blueberry, or cranberry powder for 12 weeks could improve blood sugar control and reduce symptoms in people with type 2 diabetes. 120 adults on oral diabetes medication were randomly assigned to one of the three supplements. Research…

This study tested a surgery that combines two procedures to help people with obesity and type 2 diabetes lose weight and control their blood sugar. 18 adults aged 19-65 with a BMI between 35 and 50 took part. Researchers measured weight loss and metabolic changes over time.

This study tested a new daily pill, BMF-219, in healthy adults and people with type 2 diabetes. The goal was to see if it is safe and helps lower blood sugar levels over 26 weeks. About 443 participants took either the drug or a placebo to compare results.

This study tested a diabetes pill called ertugliflozin in 166 children and teenagers aged 10 to 17 with type 2 diabetes. Participants took either the drug or a placebo for 24 weeks, along with their usual diabetes medicines. The main goal was to see if ertugliflozin could safely …

This study tested a 3-month lifestyle program, delivered by Pasifika community health workers, to help Native Hawaiians and Pacific Islanders with conditions like diabetes, high blood pressure, and obesity. The program included healthy eating and activity tips plus support for so…

This early-stage trial tested a new drug called CT-388 in 129 overweight or obese adults, including some with type 2 diabetes. The study aimed to check the drug's safety and how the body processes it, while also measuring weight loss and blood sugar changes. Participants received…

This study looked at whether adding vitamin B12 to the diabetes drug dapagliflozin improves blood sugar control in people with type 2 diabetes. Eighty volunteers took either dapagliflozin alone or dapagliflozin plus vitamin B12 for 12 months. Researchers measured HbA1c levels to …

This study tested two injectable diabetes drugs in 582 Chinese adults whose blood sugar was not well controlled with oral medications. One group received iGlarLixi (a mix of insulin and another drug), and the other received IDegAsp (a different insulin mix). The main goal was to …

This study tested a long-acting insulin called insulin glargine U300 in 570 Chinese adults with type 2 diabetes whose blood sugar was not well controlled. Some participants had never used insulin before, while others switched from another basal insulin. The main goal was to see h…

This study looked at whether a type of talk therapy (cognitive-behavioral therapy) could improve how the body uses insulin in teenage girls at risk for type 2 diabetes. The 147 participants were girls aged 12-17 with depressive symptoms and a family history of diabetes. The thera…

This study tested a long-acting insulin called glargine (brand name Toujeo) in 228 adults with type 2 diabetes whose blood sugar was still too high despite taking oral diabetes medications. The main goal was to see how safe the insulin was, including any low blood sugar episodes.…

This early-stage trial tests an experimental oral drug called XW014 in healthy volunteers and people with type 2 diabetes. The main goal is to check safety and how the body handles the drug. 127 participants will receive either the drug or a placebo in single or multiple doses. T…

This completed study tested whether adding allopurinol (a gout medication) to standard lisinopril treatment could better protect kidneys in people with type 2 diabetes. 80 patients with normal uric acid levels were split into two groups: one received both drugs, the other lisinop…

This study tested a new drug called ecnoglutide (XW003) in 211 adults with type 2 diabetes that was not well controlled by diet and exercise alone. Participants received either the drug or a placebo as a weekly injection for several weeks. The main goal was to see if the drug cou…

This study tested a new way to help people aged 60 and older with type 2 diabetes manage their condition. Instead of traditional finger-prick blood tests, participants wore a non-invasive sensor on their wrist to track glucose levels. They also received personalized coaching via …

This completed study looked at whether the diabetes drug empagliflozin (Jardiance) can help repair heart damage in diabetic patients who had a major heart attack. 200 participants took either 10 mg or 25 mg of the drug daily for 6 months. Researchers measured changes in heart siz…

This early-phase study tested an oral tablet called ecnoglutide in 87 healthy adults. The drug is a GLP-1 analogue, similar to existing injectable treatments for type 2 diabetes and obesity, but designed to be taken by mouth. The main goal was to check safety and how the body pro…

This completed Phase 4 study tested Soliqua 100/33, a once-daily injectable combining insulin and a GLP-1 drug, in 124 adults with very uncontrolled type 2 diabetes (HbA1c ≥9%) who were not yet on insulin. The goal was to see if the drug increased the time their blood sugar staye…

This Phase 3 trial tested whether adding a new drug called JW0201 to standard diabetes medications (metformin and another pill) helps lower blood sugar more effectively. The study included 196 adults with type 2 diabetes whose blood sugar was not well controlled on their current …

This Phase 3 trial tested whether adding an experimental drug called JW0201 to standard diabetes medications (metformin and empagliflozin) helps lower blood sugar more effectively. The study involved 200 adults with type 2 diabetes whose blood sugar was not well controlled on the…

This study tested whether a personalized meal plan (Individualized Dietary Plan) is practical and helpful for adults with type 2 diabetes. 122 participants were randomly assigned to either the personalized diet or standard care. The study measured adherence, blood sugar (HbA1c), …

This study tested a new device called LabPatch, a small patch worn on the arm that measures blood sugar levels continuously. Researchers compared its accuracy to standard lab tests and two commercial glucose meters. The study involved 30 adults with type 1 or type 2 diabetes to s…

This study looked at new markers in blood and urine to detect and predict the severity of drug-associated acute pancreatitis in adults. Researchers compared these markers in 175 patients with drug-induced pancreatitis, other pancreatic diseases, and healthy volunteers. The goal i…

This completed trial tested how accurately the True Vie I3 continuous glucose monitor measures blood sugar levels in 159 adults with type 1 or type 2 diabetes. Participants wore the device while researchers compared its readings to standard lab measurements. The goal was to see i…

This completed study tested a 24-month program that combined face-to-face counseling with digital tools to help families prevent and manage type 2 diabetes and high blood pressure. Over 1,200 adults and their children from Albania, Bulgaria, Greece, and Spain took part. The progr…

This completed study tested whether sending behavioral nudges through Denmark's official electronic letter system could increase flu vaccination among adults aged 18-64 with chronic diseases. Over 300,000 participants were randomly assigned to receive different types of letters o…

This study tested whether a 12-week Pilates program could improve erectile function in 60 men aged 40-60 with type 2 diabetes and erectile dysfunction. Participants did Pilates three times a week for 60 minutes each session. The study measured blood flow in the penis and used a q…

This completed phase 1 study tested whether a weekly injection of retatrutide helps people with type 2 diabetes recover faster from low blood sugar (hypoglycemia). 80 participants on metformin and diet/exercise received either retatrutide or a placebo for 16 weeks. Researchers me…

This study looked at whether adding foot exercises to aerobic exercise helps people with type 2 diabetes and nerve damage in their legs. 74 participants were split into three groups: usual medical care, aerobic exercise only, or aerobic exercise plus foot exercises. The goal was …

This study looked at whether a diabetes education program plus cinnamon supplements could help adults with type 2 diabetes who have painful nerve damage in their feet. Sixty-two participants were split into two groups and followed for six months. Researchers measured changes in b…

This study tested whether a marching exercise combined with mental tasks (like counting backwards) can improve physical performance, thinking, and heart health in older adults with type 2 diabetes. Sixty participants were split into two groups: one did the combined exercise and c…

This study tested a mobile health program designed to support family caregivers of people with both dementia and diabetes. The program added weekly online support and resources to standard home visits. Researchers measured changes in caregiver burden and social support after 12 w…

This study tested whether shivering from cold exposure can improve 24-hour blood sugar levels in people with prediabetes or type 2 diabetes. Twenty-four participants underwent two cold sessions at different shivering intensities. The goal was to see if muscle activation from shiv…

This completed study looked at how inflammation might connect heart disease and diabetes. Researchers used PET scans and blood tests to measure inflammation in 150 adults, including healthy volunteers. The goal was to better understand these links, not to test a new treatment.

This completed study looked at how well Danish hospitals followed official guidelines for managing blood sugar in people with diabetes who had major, non-cardiac surgery. Researchers reviewed records from over 13,000 patients treated between 2017 and 2023. They focused on whether…

This study checked how well two continuous glucose monitors (Dexcom G6 and FreeStyle Libre) work when oxygen levels are low. Thirty people with type 1 or type 2 diabetes took part. Researchers compared sensor readings to blood tests during controlled low-oxygen conditions to see …

This completed study observed 40 people with type 2 diabetes to find blood markers that could identify those at risk for a serious liver condition called NASH. Researchers measured liver stiffness and calculated scores like FIB-4 and ELF to see which patients might have liver sca…

This study tested whether an educational video and action plan, called 'Prepare for Your Diabetes Care,' could help older adults (75+) with type 2 diabetes reduce their risk of dangerously low blood sugar. Over 12 months, 669 participants were randomly assigned to receive the int…

This early-stage study looked at how two different tablet versions of the experimental diabetes drug HRS-7535 are absorbed in the body, and whether food changes that. It involved 24 healthy adults who took the tablets under fasting and fed conditions. The goal was to compare the …

This study tested a program where doctors refer inactive people with chronic diseases (like diabetes, heart disease, or obesity) to an exercise professional for personalized counseling. The goal was to see if this referral scheme helps people become more active compared to just g…

This completed Phase 1 trial tested how four diabetes medications (HRS-1780, henagliflozin, metformin, and HRS-7535) affect each other's levels in the body. Twenty-four healthy men took the drugs in a fixed order, and researchers measured drug concentrations and side effects. The…

This completed study analyzed electronic health records from over 6,500 patients in China who started taking finerenone for chronic kidney disease and type 2 diabetes. Researchers tracked kidney function, potassium levels, and side effects like high potassium. The goal was to see…

This study looked at how the amount of salt in the diet changes the effects of the diabetes drug ertugliflozin on blood pressure and kidney function. Overweight adults with type 2 diabetes followed either a low-salt or high-salt diet while taking the drug or a placebo. The goal w…

This study looked at data from 348 people with type 2 diabetes in Germany who use the myTherapy app. Researchers wanted to see how many had high levels of a protein called albumin in their urine, which is a sign of kidney damage. They also tracked how these levels changed over a …

This study combines data from four earlier trials to track 262 adults with type 2 diabetes and obesity for up to 13 years. Researchers want to see if bariatric surgery keeps blood sugar under control longer than medical or lifestyle changes. Participants were originally in random…

This study looks at whether metformin, a standard diabetes medicine, can improve thinking and memory in older adults with type 2 diabetes by altering their gut bacteria. Fifty participants aged 55 to 80 will be followed for a year, with half taking metformin for six months. Resea…

This study tested five different blood glucose meters in 501 adults with type 1 or type 2 diabetes who use insulin. Participants used multiple devices to see how accurate and reliable each meter is in real-world conditions. The goal was to help people with diabetes and their doct…

This study compared two types of gastric bypass surgery in 40 adults with obesity and type 2 diabetes. Researchers measured changes in gut hormones like GLP-1 to see which surgery better improves insulin resistance and diabetes. The goal was to understand how each surgery affects…

This study tested a personalized medicine approach in 239 people with type 2 diabetes who use multiple daily insulin injections. Researchers used blood tests (C-peptide and GAD antibodies) to see if some patients could safely stop their mealtime insulin and switch to other diabet…

This study looked at whether giving a carbohydrate drink (yogurt with honey) before elective abdominal surgery is safe and helpful for people with type 2 diabetes. 120 patients were split into three groups: non-diabetic controls, non-diabetic with the drink, and diabetic with the…

This study looked at whether a special education program could help people with diabetic foot (a serious complication of type 2 diabetes) become more prepared for disasters like earthquakes or floods. 68 patients took part, with some receiving the education and others getting usu…

This study looked at 100 people aged 40 and older who had cataract surgery. Half had type 2 diabetes and half did not. Researchers measured changes in the thin cell layer on the inside of the cornea before and after surgery to see if diabetes affects recovery. The goal is to help…

This study examined whether type 2 diabetes influences how well a dental procedure called pulpotomy works in adults. Researchers compared 70 diabetic and non-diabetic patients who had a molar treated for irreversible pulpitis. They checked the tooth's health, symptoms, and X-ray …

This study looked at whether a generative AI simulation can improve how medical students communicate a type 2 diabetes diagnosis. 120 students were split into two groups: one used the AI tool, the other used traditional methods. Researchers measured changes in communication skill…

This study looked at 186 pregnant women with type 1 or type 2 diabetes to understand how fats in the blood relate to baby birth weight. Researchers measured blood fats, diet, and placenta genes. The goal is to find new ways to prevent babies from being born too large, which can c…

This completed study used a special eye scan called OCTA to look at tiny blood vessels in the retina of 200 people with type 2 diabetes who had no signs of eye disease on a standard exam. The goal was to see if the duration of diabetes affects these vessels. The findings could he…

This study looked at how common and severe fatty liver disease is in people with type 2 diabetes. Researchers used advanced MRI scans to measure liver fat, inflammation, and scarring. 317 patients were checked twice, three years apart, to see how the disease changes over time. Th…

This completed study looked at how muscle size and strength change in older adults with type 2 diabetes during bed rest and exercise. Researchers studied 95 participants to find targets for future treatments to prevent muscle loss and disability. The goal is to improve health and…

This study looked at whether using a blood marker called glycated albumin (GA) to guide diabetes treatment works better than the usual HbA1c test. 200 adults newly diagnosed with type 2 diabetes were split into two groups: one where doctors used GA levels to adjust medication, an…

This study looked at whether the incremental shuttle walk test (a walking test that gets faster over time) is a valid and reliable way to measure exercise capacity in 120 people with type 2 diabetes. Participants did the test twice, one week apart, and also did a standard six-min…

This completed study looked at 542 adults to see if having more leg fat is linked to a lower risk of type 2 diabetes, and whether belly fat plays a role in that link. Researchers used body scans and statistical models to explore these connections separately for men and women. The…

This study followed 245 people with type 2 diabetes and high heart risk for two years to see how many develop heart failure. Researchers collected data from doctor visits and phone calls to track heart health over time. The goal was to better understand who is at risk and how the…

This study looked at nearly 242,000 adults with type 2 diabetes to compare different glucose-lowering medications and their effects on heart health. The goal was to help patients and doctors choose the best treatment based on age, sex, race, and kidney function. The main focus wa…

This study looked at whether continuous glucose monitors (CGMs) can help predict low blood sugar (hypoglycemia) in adults with type 2 diabetes. 41 participants wore either a regular CGM or a hidden one for a period of time. The goal was to compare how often low blood sugar occurr…

This study tracked over 1,000 adults with type 2 diabetes in Vietnam who were prescribed dapagliflozin (Forxiga) as part of routine care. Researchers monitored side effects and serious events over 24 weeks to confirm the drug's safety in real-world use. The goal was to support th…

This study tested whether simple electronic reminders in doctors' computer systems could reduce unnecessary tests and treatments for older adults. Researchers focused on three common issues: testing for bacteria in urine without symptoms, PSA tests for older men without prostate …

This study looked at how raising ketone levels in the blood affects heart function and sugar use in 41 adults with type 2 diabetes and mild-to-moderate heart failure. Researchers used MRI and PET scans to measure heart pumping and energy use. The goal was to understand the body's…

This study looked at 120 adults with type 2 diabetes and gum disease to see how well their blood sugar was controlled and how it related to the severity of gum problems and cavities. Researchers measured gum health, tooth decay, and HbA1c levels (a measure of blood sugar control)…

This study looked at whether the diabetes drug metformin can be used safely in people with type 2 diabetes who also have kidney disease. Researchers gave increasing doses of metformin to 82 patients with different stages of kidney failure and measured the drug levels in their red…

This completed study followed 24 adults with type 2 diabetes who use insulin pumps. Participants wore a continuous glucose monitor for 14 days at home to track blood sugar levels. The goal was to see how glucose levels relate to insulin doses and meals in everyday conditions. It …

This completed study looked at whether people with type 2 diabetes who show signs of premature aging (like shortened telomeres) are more likely to develop heart muscle disease. Researchers used heart scans and blood tests in 150 adults aged 40-55 with diabetes but no heart sympto…