TYPE 2 DIABETES MELLITUS

This study tested whether a weekly injection of the diabetes medication exenatide could help protect the heart and kidneys in people with type 2 diabetes who were at risk for heart problems and had mildly reduced kidney function. For 38 weeks, some participants received the real …

This study tested how well a drug called MP-513 controls blood sugar levels throughout the day in people with type 2 diabetes. Japanese adults with diabetes took the drug for 4 weeks while researchers measured their blood sugar responses to meals. The goal was to see if this medi…

This small, completed trial tested a new type of weight loss surgery for people with both obesity and type 2 diabetes. The procedure combined two surgical techniques to see if it could help patients lose weight and improve their diabetes control. Researchers monitored 18 particip…

This early-stage study tested the safety and effects of a new oral medication called XW014 for type 2 diabetes. It involved 127 healthy volunteers and people with type 2 diabetes, who received either the drug or a placebo. The main goal was to see how the body processes the drug …

This study tested whether a medication called Soliqua could help people with very poorly controlled type 2 diabetes spend more time with their blood sugar in a safe, healthy range. For 16 weeks, 124 participants who were not yet on insulin wore a continuous glucose monitor to tra…

This study compared the effectiveness and safety of four different drug combinations, all containing metformin, for people newly diagnosed with type 2 diabetes. It involved 172 adults who took one of the combinations daily for 90 days. The goal was to see which mix best controlle…

This study tested the long-term safety and effectiveness of adding canagliflozin (a pill) to insulin therapy for Japanese adults with type 2 diabetes. The 139 participants had already completed a 16-week study and took the medication for an additional 36 weeks. Researchers measur…

This study tested a new oral medication called TA-7284 for people with type 2 diabetes. Researchers followed nearly 1,300 Japanese patients for one year to see how safe and effective the medication was, either alone or combined with other diabetes drugs. The goal was to help cont…

This study compared the effectiveness and safety of two injectable diabetes treatments, iGlarLixi and IDegAsp, in Chinese adults. The 582 participants had type 2 diabetes that wasn't well controlled with oral medications alone. Over 24 weeks, researchers measured which treatment …

This study tested whether adding a pill called canagliflozin to insulin therapy helps control blood sugar better in adults with type 2 diabetes. It involved 146 Japanese patients whose blood sugar was still too high despite using insulin, diet, and exercise. Participants took eit…

This study compared two different insulin injection schedules to see which one better controls blood sugar in people with type 2 diabetes. Over 200 adults already using insulin tried either two daily injections of a combined insulin or one injection of that insulin plus two extra…

This study tested whether a new drug called HTD1801 could help adults with type 2 diabetes better control their blood sugar when metformin alone wasn't enough. Over 550 participants were randomly assigned to receive either HTD1801 or a placebo (a dummy pill) for 24 weeks, followe…

This study tested whether adding a new drug called MP-513 to the common diabetes medication metformin could help control blood sugar levels better. It involved 448 adults with type 2 diabetes who were already taking metformin. Researchers compared four different doses of MP-513 o…

This study aimed to check the long-term safety and effectiveness of the diabetes drug Teneligliptin (MP-513) over one year. It involved 240 Japanese adults with type 2 diabetes, who took the drug either by itself or alongside another common diabetes medication. Researchers tracke…

This study tested whether adding the drug ertugliflozin could help teens (ages 10-17) with type 2 diabetes better control their blood sugar. It involved 166 young people who were already taking metformin, with or without insulin. The main goal was to see if the new drug was safe …

This study tested the safety and effectiveness of adding the drug canagliflozin to existing GLP-1 therapy for one year in Japanese adults with type 2 diabetes. It involved 71 participants whose blood sugar was not well controlled on their current treatment. The goal was to see if…

This study tested whether adding a new drug called Teneligliptin to an existing diabetes medication (pioglitazone) could better control blood sugar in Japanese adults with type 2 diabetes. It involved 204 participants who took the drug combination for up to 52 weeks. The main goa…

This study tested whether the drug teneligliptin helps control blood sugar in adults with type 2 diabetes. 254 Chinese participants were randomly assigned to receive either the drug or a placebo pill for 24 weeks while continuing their usual diet and exercise. Researchers measure…

This study tested whether an experimental drug called AMG 133 could help people lose weight and keep it off for a year. Nearly 600 adults with obesity, some of whom also had type 2 diabetes, received either the drug or a placebo injection. Researchers measured how much weight par…

This study tested whether personalized meal plans could help people with type 2 diabetes better manage their condition. Researchers worked with 122 adults in Pakistan to see if customized diet advice was practical to follow and could improve blood sugar and cholesterol levels ove…

This study tested an investigational drug called CT-868 to see if it could help lower blood sugar and reduce body weight in adults with type 2 diabetes who are also overweight or obese. Over 100 participants received either the drug or a placebo for 26 weeks. The main goal was to…

This study tested a new oral medication called BMF-219 in healthy adults and adults with type 2 diabetes. The main goals were to check the drug's safety and how it affects blood sugar levels over time. Researchers gave different doses to see how well the body handles the drug and…

This early-stage study tested the safety of a new oral medication called ecnoglutide in 87 healthy adults. The medication is being developed to help manage type 2 diabetes and obesity. Researchers gave participants increasing doses to check for side effects and see how the body p…

This study tested if adding a new drug called Teneligliptin (MP-513) to an existing Sulfonylurea medication was safe and effective for controlling blood sugar in Japanese adults with type 2 diabetes. It involved 194 participants and measured changes in key blood sugar markers ove…

This study aimed to see if the medication dapagliflozin works better than standard care for managing type 2 diabetes. It involved over 600 adults whose diabetes was not well-controlled on their first medication. Researchers compared the two approaches over two years, looking at b…

This study tested a lifestyle program designed specifically for Native Hawaiian and Pacific Islander communities to help control chronic health conditions like diabetes, high blood pressure, and high cholesterol. The program combined nutrition and exercise coaching with support f…

This study tested a new oral medication called TA-7284 for people with type 2 diabetes whose blood sugar wasn't well controlled by diet and exercise alone. For 12 weeks, 383 participants took either the new drug or a placebo (a pill with no medicine) to see if it safely lowered b…

This study tested whether adding a pill called teneligliptin to insulin therapy helps control blood sugar better in Japanese adults with type 2 diabetes. It involved 148 participants who were already on a stable insulin dose. Researchers measured changes in key blood sugar marker…

This study tested a new weekly injection called CagriSema to see if it helps people with obesity and type 2 diabetes lose weight and better control their blood sugar. About 1,200 participants were randomly assigned to receive either the real medicine or a placebo (dummy medicine)…

This study tested a new medicine called JW0201 for people with type 2 diabetes whose blood sugar was still too high despite taking other specific medications. About 196 participants were randomly assigned to receive either the new drug or a placebo (a dummy pill) for 24 weeks. Th…

This study tested the long-term safety and effectiveness of the drug Teneligliptin (MP-513) for managing type 2 diabetes. It involved 462 Japanese patients who took the drug alone or alongside their usual diabetes pills for 52 weeks. The main goal was to see how safe the drug was…

This study tested whether injections of a patient's own processed kidney cells (called REACT) could safely slow the worsening of kidney function in people with diabetes and chronic kidney disease. It involved 53 participants who received up to two injections into their kidneys an…

This study tested whether interacting with live turtles or watching turtle videos could help adults with type 2 diabetes. Researchers wanted to see if this 'pet therapy' could improve long-term blood sugar control and boost people's confidence in managing their medication. They c…

This study tested the safety and effectiveness of giving two diabetes drugs together for a full year. It involved 153 Japanese adults with type 2 diabetes whose blood sugar was not well controlled on one of the drugs alone. Researchers measured side effects, changes in long-term …

This study tested the safety and effectiveness of a long-acting insulin called Gla-300 in adults with type 2 diabetes. It involved 228 people whose blood sugar was not well controlled despite taking diabetes pills. The goal was to see if adding this once-daily insulin injection w…

This study tested whether adding the drug canagliflozin to an existing medication (teneligliptin) could help Japanese adults with type 2 diabetes who still had high blood sugar. For 24 weeks, researchers measured changes in long-term blood sugar levels (HbA1c), body weight, and o…

This study looked at whether weight-loss surgery (sleeve gastrectomy) could improve the health of the pancreas, kidneys, and heart in young people (ages 12-21) with type 2 diabetes. Researchers measured organ function in about 50 participants before and after surgery to understan…

This large, completed study tested a new weekly medicine called CagriSema, which combines two drugs, for people with type 2 diabetes. It aimed to see if the combination works better than either drug alone or a placebo at lowering blood sugar and body weight. Over 2,700 adults who…

This early-stage study tested a new diabetes medication called TA-7284 to check its safety and how it affects blood sugar levels. Researchers gave the drug to 61 people with type 2 diabetes for 15 days, testing four different doses. The main goal was to see how the body processes…

This study tested whether adding a drug called teneligliptin to an existing drug, canagliflozin, could help Japanese adults with type 2 diabetes who still had high blood sugar. It involved 154 participants who took the two-drug combination once a day for 24 weeks. The main goal w…

This study tested whether a 12-week intensive exercise program could improve thinking skills, blood sugar control, and overall health in middle-aged and older adults with type 2 diabetes. Researchers enrolled 58 participants, some of whom were at higher risk for memory and thinki…

This study tested whether daily powders made from bitter melon, blueberry, or cranberry could help people manage type 2 diabetes. For 12 weeks, 120 participants took one of the powders alongside their regular medication. The results showed the powders helped lower long-term blood…

This study looked at whether adding a new drug called Zemidapa to existing diabetes medications helps control blood sugar better. It followed over 2,000 people with type 2 diabetes for 12 weeks to see if the new combination was effective and safe. The main goal was to see how muc…

This study investigated whether making people shiver from cold exposure could help control blood sugar levels. Researchers tested this in 24 adults with either pre-diabetes or type 2 diabetes. They carefully monitored participants' glucose for 24 hours after different intensities…

This study tested a personalized plan to see if some people with type 2 diabetes who take multiple daily insulin shots could safely stop their mealtime insulin. Researchers used specific blood tests to check patients' natural insulin production and then had some participants stop…

This study tested if adding a new drug called teneligliptin to the standard metformin treatment helps control blood sugar better in adults with type 2 diabetes. It involved 247 Chinese patients whose diabetes was not well-controlled on metformin alone. For 24 weeks, researchers c…

This study tested a new oral medication called TA-7284 to see if it could help control blood sugar in adults with type 2 diabetes. For 24 weeks, 272 Japanese participants whose diabetes wasn't well-managed by diet and exercise alone received either a low dose, high dose, or a pla…

This study tested whether using a newer blood test called glycated albumin (GA) helps manage type 2 diabetes better than the standard test (HbA1c). It involved 200 newly diagnosed patients in China. Doctors in one group used the GA test results to adjust medications earlier, whil…

This was an early-stage study to check the safety of a new drug called ZT002, which is being developed for type 2 diabetes. It involved 32 healthy volunteers who received either the drug or a placebo. The main goal was to see if the drug was safe and how it moved through the body…

This study tested how easy and safe it is for adults with type 2 diabetes to start using an automated insulin pump system. Fifty-six participants used the Omnipod M System, which automatically adjusts insulin, for up to 18 weeks. Researchers wanted to see if a simpler setup proce…

This study tested whether a new weekly injection called XW003 could help control blood sugar in adults with type 2 diabetes when diet and exercise alone weren't enough. For 24 weeks, participants received either XW003 or a placebo injection, followed by 28 weeks where everyone re…

This study tested whether a new medication called Teneligliptin (MP-513) could safely help control blood sugar in people with type 2 diabetes. It involved 203 Japanese adults who were managing their diabetes with diet and exercise alone. For 12 weeks, participants received either…

This study analyzed health records of over 240,000 people with type 2 diabetes to compare how different diabetes medications affect heart health. Researchers looked at four common medication classes to see which ones best prevent heart attacks, strokes, and other cardiovascular p…

This study tested how well and safely a long-acting insulin called glargine U300 worked for Chinese adults whose type 2 diabetes was not well controlled. It involved 570 participants who either started this insulin for the first time or switched to it from another insulin. Resear…

This study tested a new medicine called JW0201 for people with type 2 diabetes whose blood sugar was still too high despite taking two other specific drugs. About 200 participants were randomly assigned to receive either JW0201 or a placebo (a dummy pill) in addition to their cur…

This study tested whether a 6-week group therapy program for depression could improve the body's response to insulin and help prevent type 2 diabetes in at-risk teenage girls. Researchers compared the therapy group to a health education group and followed 147 participants for one…

This study tested whether giving diabetic patients a carbohydrate-rich drink before elective abdominal surgery is safe and helps them recover better. Researchers compared 120 patients—some with diabetes, some without—who received either the special drink or water before their ope…

This study aimed to better understand how blood sugar levels change throughout the day for people with type 2 diabetes who use an insulin pump. Researchers monitored 24 participants at home for 14 days using a continuous glucose sensor. The goal was to see how meals and insulin d…

This study aimed to understand if raising ketone levels in the blood could improve how the heart pumps in people with both type 2 diabetes and heart failure. Researchers gave 41 participants infusions of ketones at different levels and used heart scans (MRI and PET) to measure ch…

This small, early-stage study looked at how a potential diabetes drug called TA-7284 is processed by the body in people with moderate kidney problems. It compared 24 adults with type 2 diabetes who had either normal or reduced kidney function. The main goal was to understand how …

This study aimed to understand why babies born to mothers with diabetes are often larger, even when blood sugar is well-controlled. Researchers followed 186 pregnant women, including those with type 1 or type 2 diabetes and those without, to see if specific fats in the mother's a…

This study aimed to see if a continuous glucose monitor (a small sensor worn on the body) could help predict when people with type 2 diabetes are at risk for dangerously low blood sugar. 41 participants, considered at either high or low risk for these episodes, wore monitors that…

This study aimed to understand if type 2 diabetes speeds up aging in the body, which might increase the risk of developing a specific heart muscle problem called diabetic cardiomyopathy. Researchers studied 150 middle-aged adults with well-managed type 2 diabetes but no current h…

This study tested whether an educational program could help people with diabetic foot ulcers prepare for emergencies like natural disasters. 68 participants either received special training on creating emergency kits and managing foot care during crises, or received their usual c…

This study aimed to see if a specific walking test is a valid and reliable way to measure exercise capacity in people with type 2 diabetes. It involved 120 participants who performed the walking test twice, one week apart, to check for consistency. The goal was to find a simple, …

This study tested whether gentle reminders in doctors' computer systems could help reduce unnecessary medical care for older adults. Researchers focused on three common areas: overtreating diabetes, over-testing for urinary infections without symptoms, and unnecessary prostate ca…

This study tested whether a new AI simulation program could teach medical students how to communicate a type 2 diabetes diagnosis more effectively than traditional training. 120 students were randomly assigned to either practice with the AI program or use standard teaching method…