New combo pill shows promise for type 2 diabetes in japanese patients

NCT ID NCT00974090

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether adding teneligliptin to standard sulfonylurea therapy improves blood sugar control in 194 Japanese adults with type 2 diabetes. Participants received either teneligliptin or a placebo for 12 weeks, followed by an open-label extension for up to 52 weeks. The main goal was to measure changes in HbA1c, a key marker of long-term blood sugar levels.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Teneligliptin (a DPP-4 inhibitor) combined with sulfonylurea

What this could lead to

If successful, this could provide a new combination option to help people with type 2 diabetes better control their blood sugar levels.

What could go wrong

This is a completed Phase 3 trial, but results may not apply to all populations. As with any diabetes medication, there are risks of low blood sugar and other side effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Insulin Resistance type 2 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Study site

    Sapporo, Hokkaido, Japan