Simple stretching program may counteract Diabetes-Related muscle stiffness
NCT ID NCT05585502
First seen Jul 06, 2026 · Last updated Jul 07, 2026 · Updated 1 time
Summary
This study investigates whether a passive stretching program can reduce muscle and tendon stiffness in people with type 2 diabetes. Diabetes can cause muscles and tendons to become stiffer, making walking harder and increasing energy use. The trial compares stiffness in people with diabetes to healthy controls, and tests a home-based stretching routine using an elastic band to see if it can improve flexibility and movement.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- passive stretching training program (minute oscillation stretching)
- What this could lead to
- If effective, this simple stretching program could offer a new way to improve mobility and reduce walking difficulty in people with type 2 diabetes.
- What could go wrong
- This is a small, early-stage study with only 46 participants. The stretching program may not produce meaningful changes in stiffness or walking ability, and results may not apply to all people with diabetes.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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46 people
The number who actually took part.
- Started
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Dec 2022
- Finished
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Apr 2024
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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50 to 70 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * body mass index between 23 and 30 kg/m2 * moderate level of physical activity in the everyday life (assessed by means of the International Physical Activity Questionnaires, IPAQ) Exclusion Criteria: * neuropathy of nondiabetic origin * severe neuropathy * foot ulcers * arterial insufficiency * arthritis of the ankle/foot * previous foot/knee surgery * previous Achille tendon rupture * previous Charcot foot * cardiovascular and respiratory deficits that would impede the performance of the locomotion test * insulin therapy
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Sezione di Scienze Motorie
Verona, Italy, 37131, Italy
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