Diabetes drug cocktail tested in healthy volunteers
NCT ID NCT06495931
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This completed Phase 1 trial tested how four diabetes medications (HRS-1780, henagliflozin, metformin, and HRS-7535) affect each other's levels in the body. Twenty-four healthy men took the drugs in a fixed order, and researchers measured drug concentrations and side effects. The goal was to gather safety and interaction data, not to treat diabetes.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
HRS-1780, henagliflozin, metformin, and HRS-7535 tablets
What this could lead to
If successful, this study could help doctors understand how these drugs work together, potentially leading to safer combination treatments for type 2 diabetes.
What could go wrong
This is a very early, small study in healthy people, not patients. It only looks at drug levels in the body, not whether the drugs actually improve diabetes. Results may not apply to real-world patients.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for TYPE 2 DIABETES MELLITUS are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
Xuanwu Hospital ,Capital Medical University
Beijing, Beijing Municipality, 100032, China