TYPE 2 DIABETES MELLITUS

This study is testing whether testosterone gel can improve bone strength and reduce fracture risk in men who have both type 2 diabetes and low testosterone. Researchers are enrolling male veterans with both conditions to receive either the testosterone gel or a placebo gel for on…

This study is testing a new weekly medicine called retatrutide to see if it helps people with type 2 diabetes recover faster from episodes of dangerously low blood sugar. About 78 participants will receive either the real medicine or a placebo for 16 weeks. Researchers will then …

This study is testing whether a new drug called SHR-3167 works as well as or better than a standard long-acting insulin (degludec) for controlling blood sugar in people with type 2 diabetes. It involves 173 adults who are already using insulin with or without other diabetes pills…

This study is testing whether three existing diabetes medications can help reverse mild memory loss in people with type 2 diabetes. It will involve about 400 adults who have both conditions. Participants will take one of the three drugs for nearly a year and a half while research…

This study is observing how a kidney-protecting drug called finerenone is used and how safe it is for patients with chronic kidney disease and type 2 diabetes in real-world Chinese hospitals. It will track 5,000 patients' health records to see how their kidney function and potass…

This study aims to find out which of two three-drug combinations works better and is safer for people newly diagnosed with type 2 diabetes. It will involve 110 adults in Pakistan, who will take one of the two pill combinations daily for 90 days. Researchers will closely track blo…

This study is testing whether a new injectable drug called JY09 is safe and effective at lowering blood sugar in adults with type 2 diabetes. It will involve 270 people whose diabetes is not well managed by diet and exercise alone. Participants will receive either JY09 or a place…

This study is collecting real-world health records from 150,000 people in the US who have both chronic kidney disease and Type 2 diabetes. Researchers want to understand if the already-approved drug finerenone helps prevent serious heart problems like heart attacks and hospitaliz…

This study is testing whether the Omnipod M insulin pump system helps adults with type 2 diabetes manage their blood sugar. About 40 participants will use the pump system for 6 weeks while researchers closely monitor their glucose levels. The main goal is to see if the system saf…

This study aimed to test whether a 10-week lifestyle program called Lifestyle MIND could help people with serious mental illness (like schizophrenia or bipolar disorder) better manage their type 2 diabetes. Researchers planned to compare a group that started the program immediate…

This study is testing if weight-loss surgery is better than standard medication for people who are obese and have just been diagnosed with type 2 diabetes. It will compare a specific surgery (laparoscopic sleeve gastrectomy) with conventional drug therapy over several years. The …

This study is observing patients with Type 2 diabetes who are prescribed the medication enavogliflozin in their regular doctor's office. It aims to see how well the drug helps with weight loss and controlling blood sugar over 24 weeks in a real-world setting. Researchers will col…

This study aims to understand how low blood sugar affects blood vessel function and increases the risk of heart problems. Researchers are testing whether a natural gut hormone called GLP-1 can change these harmful effects. The study involves 28 adults, half with type 2 diabetes a…

This study aims to understand how the sugars and fats in breast milk differ between mothers, and how a mother's diet, health, and gut bacteria affect her milk. Researchers are observing mothers, including some with diabetes, to see how these milk components influence the developm…

This study aims to understand how aerobic exercise training might improve the health of blood vessels in older veterans who have prediabetes or type 2 diabetes. Researchers are measuring specific cells involved in blood vessel repair and overall fitness before and after an exerci…

This study is exploring whether a father's diabetes and weight can leave marks on his sperm that might influence his future children's health risks. Researchers are enrolling 40 overweight men with type 1 or type 2 diabetes to see if a 3-month lifestyle program focused on blood s…

This study aims to find out if people with prediabetes or type 2 diabetes need to push themselves hard during weight training to see better blood sugar control, or if lighter effort works just as well. Fifteen participants will try three different sessions: a high-effort workout,…

This study is observing 4,500 adults with chronic kidney disease and type 2 diabetes who are starting the medication finerenone as part of their regular doctor's care. Researchers will collect information for one year to learn how the drug is used in real-world settings, includin…

This study aims to learn more about how the drug finerenone works for people in India who have chronic kidney disease and type 2 diabetes. Researchers will look back at the medical records of about 1,200 patients who were already prescribed this approved medication. The goal is t…