Surgery vs. diet: which tames diabetes better?

NCT ID NCT01047735

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares two types of weight-loss surgery (gastric bypass and gastric banding) with an intensive diet and exercise program for controlling type 2 diabetes in moderately obese adults aged 25 to 55. The goal is to see which approach works best for improving diabetes and weight loss. It is a small, early-stage trial to test whether a larger study is possible.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Roux-en-Y Gastric Bypass surgery and Laparoscopic Adjustable Gastric Banding
What this could lead to
If successful, this could show that surgery is more effective than lifestyle changes for controlling diabetes in moderately obese patients, potentially leading to better long-term outcomes.
What could go wrong
This is a small, early feasibility study with only 69 participants, so results may not apply to everyone. Surgery carries risks like infection and nutrient deficiencies, and diabetes may not fully resolve.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • William F Gourash

    Pittsburgh, Pennsylvania, 15213, United States

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