Surgery vs. diet: which tames diabetes better?

NCT ID NCT01047735

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares two types of weight-loss surgery (gastric bypass and gastric banding) with an intensive diet and exercise program for controlling type 2 diabetes in moderately obese adults aged 25 to 55. The goal is to see which approach works best for improving diabetes and weight loss. It is a small, early-stage trial to test whether a larger study is possible.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Roux-en-Y Gastric Bypass surgery and Laparoscopic Adjustable Gastric Banding

What this could lead to

If successful, this could show that surgery is more effective than lifestyle changes for controlling diabetes in moderately obese patients, potentially leading to better long-term outcomes.

What could go wrong

This is a small, early feasibility study with only 69 participants, so results may not apply to everyone. Surgery carries risks like infection and nutrient deficiencies, and diabetes may not fully resolve.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

atherosclerosis Behavior blindness (disorder) Body Weight cardiovascular disorder Death diabetes mellitus Digestive System Diseases disease hypertensive disorder Inflammation Insulin Resistance kidney failure liver disorder metabolic dysfunction-associated steatotic liver disease morbid obesity Motor Activity myocardial infarction neoplasm Obesity obesity disorder type 2 diabetes mellitus Weight Loss

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • William F Gourash

    Pittsburgh, Pennsylvania, 15213, United States