Could a common constipation drug help diabetics?
NCT ID NCT03119584
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether linaclotide (Linzess) can improve bowel movement frequency in people with type 2 diabetes who have chronic constipation. About 23 participants will receive either the drug or a placebo for two weeks, then switch after a break. The goal is to see if the drug safely increases spontaneous bowel movements.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- linaclotide (Linzess)
- What this could lead to
- If it works, this could provide a safe, effective option for relieving chronic constipation in people with type 2 diabetes.
- What could go wrong
- This is a small, early-phase trial with only 23 participants, so results may not apply to everyone. The drug may cause side effects like diarrhea or abdominal pain.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Texas Tech University Health Sciences Center
El Paso, Texas, 79905, United States
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