Exercise may boost blood vessel function in older veterans with Pre-Diabetes

NCT ID NCT01176578

Ongoing Knowledge-focused Sponsor: Baltimore VA Medical Center Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study looks at whether 6 months of aerobic exercise can improve blood vessel health and cell function in older veterans with impaired glucose tolerance, a pre-diabetic condition. Researchers will measure changes in endothelial progenitor cells and muscle blood flow. The goal is to understand how exercise might help prevent diabetes-related complications.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Aerobic exercise training
What this could lead to: If successful, this study could show that regular aerobic exercise improves blood vessel health and glucose metabolism in older adults at risk for diabetes.
What could go wrong: This is an early-stage observational study with only 70 participants, so results may not apply to everyone. Exercise adherence and individual health differences could affect outcomes.

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Conditions

The condition(s) this trial relates to.

type 2 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

TYPE 2 DIABETES MELLITUS

Contacts and locations

Locations

Baltimore VA Medical Center

Baltimore, Maryland, 21201, United States

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