Weekly shot may shield pancreas and slash liver fat in at-risk teens

NCT ID NCT05067621

First seen Apr 30, 2026 · Last updated Jun 05, 2026 · Updated 5 times

Summary

This study tests whether a weekly injection of semaglutide can help preserve the pancreas's ability to make insulin and reduce fat buildup in the liver. It involves 60 obese teenagers with prediabetes or early type 2 diabetes who also have fatty liver disease. Participants receive the drug or a placebo for 6 months, and researchers measure changes in insulin function and liver fat using special scans and glucose tests.

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Contacts and locations

Locations

  • Pediatric Diabetes Center

    New Haven, Connecticut, 06511, United States

Conditions

Explore the condition pages connected to this study.