Can a weekly diabetes drug speed recovery from dangerous low blood sugar?

NCT ID NCT06982846

Completed Symptom relief Sponsor: Eli Lilly and Company Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This completed phase 1 study tested whether a weekly injection of retatrutide helps people with type 2 diabetes recover faster from low blood sugar (hypoglycemia). 80 participants on metformin and diet/exercise received either retatrutide or a placebo for 16 weeks. Researchers measured how quickly blood sugar returned to a safe level after being lowered in a controlled setting.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: retatrutide (a weekly injection)
What this could lead to: If it works, this could show that retatrutide helps people with type 2 diabetes recover more quickly from dangerously low blood sugar.
What could go wrong: This is a small, early-phase trial (80 people) that measures a specific lab response, not real-world outcomes. The results may not apply to all patients or lead to a new treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for TYPE 2 DIABETES MELLITUS are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

type 2 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

TYPE 2 DIABETES MELLITUS

Contacts and locations

Locations

Medizinische Universität Graz

Graz, 8010, Austria

More trials for these conditions

Other studies related to the condition(s) this trial covers.