Personalized diabetes care: study tests if some patients can safely ditch mealtime insulin
NCT ID NCT06148376
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested a personalized medicine approach in 239 people with type 2 diabetes who use multiple daily insulin injections. Researchers used blood tests (C-peptide and GAD antibodies) to see if some patients could safely stop their mealtime insulin and switch to other diabetes treatments. Participants wore a continuous glucose monitor and were followed for 6 months to check blood sugar control, safety, and quality of life.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- discontinuation of prandial insulin and switch to other diabetes treatments if indicated
- What this could lead to
- If successful, this could help doctors personalize diabetes care by safely reducing insulin injections for some patients, simplifying their treatment.
- What could go wrong
- This is an observational study, not a controlled trial, so results may not be definitive. The approach may only work for a subset of patients and requires careful monitoring.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Centres Atenció Primària Lleida, Alt Pirineu i Aran
Lleida, Spain
-
Hospital Universitari Arnau de Vilanova
Lleida, 25198, Spain
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