Personalized diabetes care: study tests if some patients can safely ditch mealtime insulin

NCT ID NCT06148376

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested a personalized medicine approach in 239 people with type 2 diabetes who use multiple daily insulin injections. Researchers used blood tests (C-peptide and GAD antibodies) to see if some patients could safely stop their mealtime insulin and switch to other diabetes treatments. Participants wore a continuous glucose monitor and were followed for 6 months to check blood sugar control, safety, and quality of life.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

discontinuation of prandial insulin and switch to other diabetes treatments if indicated

What this could lead to

If successful, this could help doctors personalize diabetes care by safely reducing insulin injections for some patients, simplifying their treatment.

What could go wrong

This is an observational study, not a controlled trial, so results may not be definitive. The approach may only work for a subset of patients and requires careful monitoring.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

type 2 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Centres Atenció Primària Lleida, Alt Pirineu i Aran

    Lleida, Spain

  • Hospital Universitari Arnau de Vilanova

    Lleida, 25198, Spain