Simpler insulin regimen may work just as well for diabetes

NCT ID NCT05417841

Completed Disease control Sponsor: Beijing Hospital Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested two ways of taking insulin in people with type 2 diabetes. One group took a mix of long- and fast-acting insulin twice a day. The other group took the mix once a day plus extra fast-acting insulin at meals. After 16 weeks, researchers compared blood sugar control and safety. The goal was to see if the simpler twice-daily schedule is just as effective.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Insulin degludec and insulin aspart (a mix of long- and fast-acting insulin)
What this could lead to: If successful, this could show that a simpler twice-daily insulin mix works as well as a more complex schedule, making diabetes management easier for patients.
What could go wrong: This is a completed trial with 218 participants, so results are available but not yet widely published. The benefit is about convenience, not a cure, and individual responses may vary.

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Conditions

The condition(s) this trial relates to.

type 2 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

TYPE 2 DIABETES MELLITUS

Contacts and locations

Locations

Aerospace general hospital

Beijing, China
Beijing Boai Hospital

Beijing, China
Beijing Hospital

Beijing, China
Hebei General Hospital

Shijiazhuang, Hebei, China
Jilin University Sino-Japanese Friendship Hospital

Changchun, Jilin, China
Peking university shougang hospital

Beijing, China
The Second Affiliated Medical College of Xi'an Jiaotong University

Xi'an, Shaanxi, China

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