New daily pill could help millions shed pounds

NCT ID NCT07667803

Not yet recruiting Disease control Sponsor: AstraZeneca Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase 3 trial is testing a new daily pill called elecoglipron for weight loss in 4500 adults who are obese or overweight, with or without type 2 diabetes. Participants will take the pill or a placebo for 72 weeks, alongside diet and exercise. The main goal is to see how much weight they lose.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Elecoglipron (a daily pill)

What this could lead to

If it works, this could offer a new daily pill for significant weight loss in people with obesity or overweight, including those with type 2 diabetes.

What could go wrong

This is a large phase 3 trial, but it's still experimental. The drug may not work as hoped, could have side effects, or may not be better than existing treatments.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

obesity disorder type 2 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

WEIGHT MANAGEMENT

Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

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Birmingham, Alabama, 35205, United States
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Chandler, Arizona, 85225, United States
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Lincoln, California, 95648, United States
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Clearwater, Florida, 33765, United States
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Woodstock, Georgia, 30189, United States
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Indianapolis, Indiana, 46254, United States
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Louisville, Kentucky, 40213, United States
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Baltimore, Maryland, 21229, United States
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Potomac, Maryland, 20854, United States
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Ypsilanti, Michigan, 48197, United States
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Kansas City, Missouri, 64114, United States
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Albany, New York, 12205, United States
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Laurelton, New York, 11413, United States
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Greensboro, North Carolina, 27408, United States
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Raleigh, North Carolina, 27609, United States
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Rocky Mount, North Carolina, 27804, United States
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Statesville, North Carolina, 28625, United States
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Dayton, Ohio, 45424, United States
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Tulsa, Oklahoma, 74133, United States
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DuBois, Pennsylvania, 15801, United States
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Newport, Pennsylvania, 17074, United States
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Gaffney, South Carolina, 29340, United States
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Franklin, Tennessee, 37067, United States
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Knoxville, Tennessee, 37912, United States
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Dallas, Texas, 75254, United States
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Morgantown, West Virginia, 26501, United States
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Buenos Aires, C1425AGC, Argentina
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CABA, C1061, Argentina
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CABA, C1120AAC, Argentina
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San Nicolás, B2900DMH, Argentina
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Botany, 2019, Australia
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Malvern, 3144, Australia
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St Albans, 3021, Australia
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St Leonards, 2065, Australia
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Belém, 66073-005, Brazil
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Campinas, 13060-080, Brazil
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Curitiba, 80045-170, Brazil
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Fortaleza, 60430-350, Brazil
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São Paulo, 01228-000, Brazil
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São Paulo, 01236-030, Brazil
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São Paulo, 04012-180, Brazil
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Calgary, Alberta, T2V 4J2, Canada
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Moncton, New Brunswick, E1G 1A7, Canada
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Truro, Nova Scotia, B2N 1L2, Canada
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Brampton, Ontario, L6T 0G1, Canada
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Niagara Falls, Ontario, L2H 1H5, Canada
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North York, Ontario, M6B 3H7, Canada
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Stouffville, Ontario, L4A1H2, Canada
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Toronto, Ontario, M6G 1M2, Canada
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Toronto, Ontario, M9V 4B4, Canada
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Terrebonne, Quebec, J6X 4P7, Canada
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Araucania, 4781151, Chile
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Las Condes, 7560908, Chile
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Osorno, 5311092, Chile
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Providencia, 7500504, Chile
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Santiago, 7691236, Chile
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Santiago, 8241479, Chile
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Santiago, 8330034, Chile
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Santiago, 8331143, Chile
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Temuco, 4810345, Chile
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Bialystok, 15-375, Poland
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Bialystok, 15-435, Poland
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Bydgoszcz, 85-796, Poland
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Kielce, 25-355, Poland
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Krakow, 30-727, Poland
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Krakow, 31-261, Poland
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Krakow, 31-271, Poland
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Lodz, 90-338, Poland
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Lublin, 20-064, Poland
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Lublin, 20-718, Poland
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Poznan, 60-354, Poland
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Poznan, 60-589, Poland
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Radom, 26-600, Poland
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Warsaw, 00-124, Poland
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Warsaw, 02-507, Poland
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Warsaw, 02-758, Poland
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Bellville, 7530, South Africa
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Bloemfontein, 9301, South Africa
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Cape Town, 7500, South Africa
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Cape Town, 7764, South Africa
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Chatsworth, 4092, South Africa
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Claremont, 7708, South Africa
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Durban, 4091, South Africa
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eMkhomazi, 4170, South Africa
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Extension 8, Lenasia, 1827, South Africa
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Johannesburg, 2113, South Africa
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Midrand, 1685, South Africa
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Wentworth, 4032, South Africa
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Busan, 49201, South Korea
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Busan, 49241, South Korea
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Daegu, 42415, South Korea
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Goyang-si, 13620, South Korea
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Gyeonggi-do, 13620, South Korea
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Incheon, 21565, South Korea
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Jongno-gu, 110-746, South Korea
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Seoul, 02447, South Korea
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Seoul, 120-752, South Korea
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Suwon, 443-721, South Korea
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Changhua, 500, Taiwan
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Kaohsiung City, 807, Taiwan
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Taichung, 402, Taiwan
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Taichung, 40447, Taiwan
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Taichung, 40705, Taiwan
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Taichung, 433004, Taiwan
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Tainan, 704, Taiwan
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Tainan County, 71044, Taiwan
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Taipei, 10002, Taiwan
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Taipei, 110, Taiwan
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Adana, 01060, Turkey (Türkiye)
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Adana, 01120, Turkey (Türkiye)
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Adapazarı, 54290, Turkey (Türkiye)
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Ankara, 06530, Turkey (Türkiye)
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Ankara, 5000, Turkey (Türkiye)
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Ankara, 6230, Turkey (Türkiye)
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Antalya, 07059, Turkey (Türkiye)
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Istanbul, 34098, Turkey (Türkiye)
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Istanbul, 34384, Turkey (Türkiye)
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Istanbul, 34722, Turkey (Türkiye)
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Blackpool, FY3 7EN, United Kingdom
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Chesterfield, S40 4AA, United Kingdom
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Corby, NN17 2UR, United Kingdom
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Glasgow, G51 4TF, United Kingdom
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Hounslow, TW3 3LN, United Kingdom
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Leicester, Le5 4PW, United Kingdom
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Metropolitan Borough of Wirral, CH48 5AA, United Kingdom
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Poole, BH16 5PW, United Kingdom
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Rotherham, S65 1DA, United Kingdom
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Soham, CB7 5JD, United Kingdom
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Stowmarket, IP142SY, United Kingdom
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Wansford, PE8 6PL, United Kingdom
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Witney, OX28 6JS, United Kingdom
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Yate, BS37 4AX, United Kingdom