New pill combo aims to tame type 2 diabetes

NCT ID NCT07662044

Recruiting now Disease control Sponsor: AstraZeneca Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Aug 05, 2026 · Updated 4 times

Summary

This study tests an experimental drug called elecoglipron, taken alone or together with the existing medication dapagliflozin, in adults with type 2 diabetes whose blood sugar is not well controlled. About 800 participants will receive either the new drug, a placebo, or a combination, and researchers will track changes in blood sugar levels, weight, and safety over time. The goal is to see if elecoglipron offers a new way to manage diabetes effectively.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: elecoglipron and dapagliflozin
What this could lead to: If successful, this could provide a new oral medication option to help people with type 2 diabetes better control their blood sugar and possibly lose weight.
What could go wrong: This is a phase 3 trial, but results may not apply to all patients. Side effects are possible, and the drug may not prove superior to existing treatments.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

type 2 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

TYPE 2 DIABETES MELLITUS

Contacts and locations

Locations

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Birmingham, Alabama, 35205, United States
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Daphne, Alabama, 36526, United States
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Lomita, California, 90717, United States
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Los Alamitos, California, 90720, United States
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San Diego, California, 92111, United States
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Walnut Creek, California, 94598, United States
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Englewood, Colorado, 80110, United States
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Bridgeport, Connecticut, 06606, United States
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Jacksonville, Florida, 32256, United States
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Orlando, Florida, 32801, United States
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Conyers, Georgia, 30094, United States
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Decatur, Georgia, 30030, United States
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Hinesville, Georgia, 31313, United States
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El Dorado, Kansas, 67042, United States
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Newton, Kansas, 67114, United States
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Lexington, Kentucky, 40509, United States
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Mandeville, Louisiana, 70471, United States
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Bowie, Maryland, 20715, United States
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Southfield, Michigan, 48075, United States
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Kansas City, Missouri, 64111, United States
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St Louis, Missouri, 63141, United States
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Las Vegas, Nevada, 89119, United States
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Anderson, South Carolina, 29621, United States
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Knoxville, Tennessee, 37909, United States
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Fort Worth, Texas, 76135, United States
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Irving, Texas, 75061, United States
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Renton, Washington, 98057, United States
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Buenos Aires, C1425AGC, Argentina
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CABA, C1120AAC, Argentina
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Caba, C1128AAF, Argentina
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Ciudad de Buenos Aires, C1094AAD, Argentina
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Mar del Plata, B7600GNY, Argentina
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San Nicolás, B2900DMH, Argentina
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San Vicente, 5006, Argentina
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Santa Fe, S3000FWO, Argentina
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Baotou, 014030, China
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Binzhou, 256606, China
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Cangzhou, 061002, China
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Changsha, 430033, China
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Chengdu, 610081, China
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Ganzhou, 341099, China
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Haikou, 570208, China
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Hangzhou, 310006, China
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Huangshi, 435000, China
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Huzhou, 313003, China
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Jinan, 250013, China
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Jinzhou, 121002, China
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Lanzhou, 730000, China
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Lianyungang, 222023, China
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Liaocheng, 252000, China
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Liuzhou, 545006, China
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Loudi, 417099, China
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Luoyang, 471001, China
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Luoyang, 471003, China
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Nanchang, 330006, China
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Nanjing, 2100008, China
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Nanjing, 211100, China
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Nanyang, 473000, China
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Ningbo, 315010, China
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Panjin, 124000, China
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Qingdao, 266035, China
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Sanmenxia, 472000, China
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Shanghai, 200040, China
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Suining Shi, 629000, China
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Tonghua, 134000, China
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Xi'an, 710077, China
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Xiangtan, 411100, China
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Xuancheng, 242000, China
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Yibin, 610500, China
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Yichang, 443003, China
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Yuncheng, 044099, China
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Zhengzhou, 450002, China
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Zhengzhou, 450012, China
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Zhenjiang, 212002, China
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Gandrup, 9362, Denmark
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Herlev, 2730, Denmark
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Hillerød, 3400, Denmark
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Hvidovre, 2650, Denmark
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Athens, 10676, Greece
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Athens, 11526, Greece
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Athens, 12131, Greece
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Athens, 15125, Greece
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Heraklion, 71500, Greece
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Piraeus, 18454, Greece
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Piraeus, 18536, Greece
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Thessaloniki, 54636, Greece
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Thessaloniki, 57001, Greece
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Thessaloniki, 57010, Greece
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Budapest, 1027, Hungary
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Budapest, 1036, Hungary
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Budapest, 1138, Hungary
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Debrecen, 4032, Hungary
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Dunaújváros, 2400, Hungary
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Szeged, 6725, Hungary
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Szolnok, 5000, Hungary
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Amagasaki-shi, 660-8550, Japan
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Chiba, 261-0004, Japan
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Chitose-shi, 066-0032, Japan
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Chūōku, 1040031, Japan
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Koga-shi, 306-0232, Japan
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Minatoku, 105-0004, Japan
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Okayama, 701-1192, Japan
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Oyama-shi, 323-0022, Japan
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Shinjuku-ku, 169-0072, Japan
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Zentsuji-shi, 765-0071, Japan
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Bratislava, 81108, Slovakia
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Bratislava, 831 03, Slovakia
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Košice, 04001, Slovakia
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Martin, 036 01, Slovakia
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Námestovo, 02901, Slovakia
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Poprad, 05845, Slovakia
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Rožňava, 048 01, Slovakia
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Brackenfell, 7560, South Africa
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Cape Town, 7500, South Africa
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Cape Town, 7570, South Africa
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Claremont, 7708, South Africa
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Durban, 4093, South Africa
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eMkhomazi, 4170, South Africa
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Johannesburg, 1827, South Africa
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KwaDukuza, 4449, South Africa
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Paarl, 7646, South Africa
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Pretoria, 2, South Africa
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Jongno-gu, 110-746, South Korea
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Seongnam-si, 463-712, South Korea
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Seoul, 03080, South Korea
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Seoul, 5505, South Korea
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Barcelona, 08016, Spain
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Barcelona, 08020, Spain
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Barcelona, 08035, Spain
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Barcelona, 08930, Spain
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Figueres, 17600, Spain
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Seville, 41003, Spain
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Seville, 41950, Spain
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Changhua, 500, Taiwan
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Kaohsiung City, 80756, Taiwan
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Kaohsiung City, 813, Taiwan
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New Taipei City, 220, Taiwan
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Taichung, 40201, Taiwan
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Taichung, 40705, Taiwan
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Taichung, 433004, Taiwan
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Tainan, 70403, Taiwan
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Tainan County, 71044, Taiwan
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Taipei, 10002, Taiwan
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Adana, 01060, Turkey (Türkiye)
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Ankara, 06530, Turkey (Türkiye)
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Ankara, 06560, Turkey (Türkiye)
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Bursa, 16310, Turkey (Türkiye)
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Izmir, 35340, Turkey (Türkiye)
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Kayseri, 38039, Turkey (Türkiye)
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Samsun, 55139, Turkey (Türkiye)

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