New pill combo aims to tame type 2 diabetes

NCT ID NCT07662044

Not yet recruiting Disease control Sponsor: AstraZeneca Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests an experimental drug called elecoglipron, taken alone or together with the existing medication dapagliflozin, in adults with type 2 diabetes whose blood sugar is not well controlled. About 800 participants will receive either the new drug, a placebo, or a combination, and researchers will track changes in blood sugar levels, weight, and safety over time. The goal is to see if elecoglipron offers a new way to manage diabetes effectively.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

elecoglipron and dapagliflozin

What this could lead to

If successful, this could provide a new oral medication option to help people with type 2 diabetes better control their blood sugar and possibly lose weight.

What could go wrong

This is a phase 3 trial, but results may not apply to all patients. Side effects are possible, and the drug may not prove superior to existing treatments.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

type 2 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

TYPE 2 DIABETES MELLITUS

Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

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Birmingham, Alabama, 35233, United States
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Daphne, Alabama, 36526, United States
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Lomita, California, 90717, United States
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Los Alamitos, California, 90720, United States
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San Diego, California, 92111, United States
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Walnut Creek, California, 94598, United States
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Englewood, Colorado, 80110, United States
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Bridgeport, Connecticut, 06606, United States
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Jacksonville, Florida, 32256, United States
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Orlando, Florida, 32801, United States
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Conyers, Georgia, 30094, United States
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Decatur, Georgia, 30030, United States
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Hinesville, Georgia, 31313, United States
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El Dorado, Kansas, 67042, United States
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Newton, Kansas, 67114, United States
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Lexington, Kentucky, 40509, United States
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Covington, Louisiana, 70433, United States
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Bowie, Maryland, 20715, United States
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Southfield, Michigan, 48075, United States
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Kansas City, Missouri, 64111, United States
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St Louis, Missouri, 63141, United States
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Las Vegas, Nevada, 89119, United States
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Anderson, South Carolina, 29621, United States
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Knoxville, Tennessee, 37909, United States
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Irving, Texas, 75061, United States
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Renton, Washington, 98057, United States
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Buenos Aires, C1425AGC, Argentina
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CABA, C1120AAC, Argentina
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Caba, C1128AAF, Argentina
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Ciudad de Buenos Aires, C1094AAD, Argentina
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Mar del Plata, B7600GNY, Argentina
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San Nicolás, B2900DMH, Argentina
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San Vicente, 5006, Argentina
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Santa Fe, S3000FWO, Argentina
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Baotou, 014030, China
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Binzhou, 256606, China
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Cangzhou, 061002, China
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Changsha, 430033, China
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Chengdu, 610081, China
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Ganzhou, 341099, China
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Haikou, 570208, China
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Hangzhou, 310006, China
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Huangshi, 435000, China
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Huzhou, 313003, China
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Jinan, 250013, China
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Jinzhou, 121002, China
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Lanzhou, 730000, China
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Lianyungang, 222023, China
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Liaocheng, 252000, China
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Liuzhou, 545006, China
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Loudi, 417099, China
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Luoyang, 471001, China
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Luoyang, 471003, China
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Nanchang, 330006, China
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Nanjing, 2100008, China
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Nanjing, 211100, China
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Nanyang, 473000, China
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Ningbo, 315010, China
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Panjin, 124000, China
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Qingdao, 266035, China
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Sanmenxia, 472000, China
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Shanghai, 200040, China
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Suining Shi, 629000, China
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Tonghua, 134000, China
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Xi'an, 710077, China
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Xiangtan, 411100, China
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Xuancheng, 242000, China
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Yibin, 610500, China
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Yichang, 443003, China
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Yuncheng, 044099, China
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Zhengzhou, 450002, China
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Zhengzhou, 450012, China
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Zhenjiang, 212002, China
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Gandrup, 9362, Denmark
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Herlev, 2730, Denmark
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Hillerød, 3400, Denmark
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Hvidovre, 2650, Denmark
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Athens, 10676, Greece
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Athens, 11526, Greece
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Athens, 12131, Greece
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Athens, 15125, Greece
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Heraklion, 71500, Greece
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Piraeus, 18454, Greece
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Thessaloniki, 54636, Greece
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Thessaloniki, 57001, Greece
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Thessaloniki, 57010, Greece
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Budapest, 1027, Hungary
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Budapest, 1036, Hungary
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Budapest, 1138, Hungary
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Debrecen, 4032, Hungary
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Dunaújváros, 2400, Hungary
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Szeged, 6725, Hungary
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Szolnok, 5000, Hungary
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Amagasaki-shi, 660-8550, Japan
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Chiba, 261-0004, Japan
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Chūōku, 1040031, Japan
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Minatoku, 105-0004, Japan
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Okayama, 701-1192, Japan
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Shinjuku-ku, 169-0072, Japan
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Zentsuji-shi, 765-0071, Japan
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Brackenfell, 7560, South Africa
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Cape Town, 7500, South Africa
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Cape Town, 7570, South Africa
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Claremont, 7708, South Africa
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Durban, 4093, South Africa
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eMkhomazi, 4170, South Africa
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Johannesburg, 1827, South Africa
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KwaDukuza, 4449, South Africa
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Paarl, 7646, South Africa
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Pretoria, 2, South Africa
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Jongno-gu, 110-746, South Korea
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Seongnam-si, 463-712, South Korea
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Seoul, 03080, South Korea
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Seoul, 5505, South Korea
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Barcelona, 08016, Spain
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Barcelona, 08020, Spain
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Barcelona, 08035, Spain
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Barcelona, 08930, Spain
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Figueres, 17600, Spain
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Seville, 41003, Spain
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Seville, 41950, Spain
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Changhua, 500, Taiwan
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Kaohsiung City, 80756, Taiwan
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Kaohsiung City, 813, Taiwan
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New Taipei City, 220, Taiwan
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Taichung, 40201, Taiwan
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Taichung, 40705, Taiwan
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Taichung, 433004, Taiwan
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Tainan, 70403, Taiwan
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Tainan County, 71044, Taiwan
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Taipei, 10002, Taiwan
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Adana, 01060, Turkey (Türkiye)
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Ankara, 06530, Turkey (Türkiye)
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Ankara, 06560, Turkey (Türkiye)
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Bursa, 16310, Turkey (Türkiye)
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Izmir, 35340, Turkey (Türkiye)
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Kayseri, 38039, Turkey (Türkiye)
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Samsun, 55139, Turkey (Türkiye)