Heart's energy use revealed by new MRI technique in early trial
NCT ID NCT02648009
First seen Jan 31, 2026 · Last updated Jun 23, 2026 · Updated 22 times
Summary
This early-phase study tests a new MRI method that uses a special injection called hyperpolarized pyruvate to see how the heart uses energy. Researchers will scan the hearts of up to 112 people with high blood pressure, heart thickening, or heart failure. The goal is to see if this technique can show metabolic activity, which might help doctors better understand and manage heart conditions.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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St. Michael's Hospital
NOT_YET_RECRUITINGToronto, Ontario, Canada
Contact
Contact
-
Sunnybrook Health Sciences Centre
RECRUITINGToronto, Ontario, M4N 3M5, Canada
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Hyperpolarized Pyruvate (13C) Injection
What this could lead to
If successful, this imaging technique could help doctors see how the heart uses energy, potentially leading to better diagnosis and treatment of heart failure.
What could go wrong
This is a very early Phase 1 study focused on imaging, not treatment. It may not lead to any direct patient benefit, and the new method might not work as hoped in larger groups.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.