Can a daily pill tame obesity and type 2 diabetes?

NCT ID NCT07743450

Recruiting now Disease control Sponsor: Ascletis Pharma (China) Co., Limited Source: ClinicalTrials.gov ↗

First seen Aug 03, 2026 · Last updated Aug 14, 2026 · Updated 2 times

Summary

This trial is testing an experimental once-daily pill called ASC30 in adults who are overweight or have obesity and also have type 2 diabetes. The study aims to see if ASC30 can help with long-term weight loss and improve blood sugar control compared to a placebo. Participants will take either ASC30 or a dummy pill daily, and researchers will track changes in body weight, blood sugar, and other health measures.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: ASC30, an experimental oral medication taken once daily
What this could lead to: If successful, ASC30 could offer a convenient daily pill to help people with obesity and type 2 diabetes lose weight and improve blood sugar control, potentially reducing the need for injections.
What could go wrong: This is an early-stage test in a large group, and the drug may not prove more effective than placebo. Possible side effects are not yet fully known, and results may not apply to everyone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Obesity obesity disorder Overweight type 2 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CHRONIC WEIGHT MANAGEMENT OBESITY OBESITY OR OVERWEIGHT WITH TYPE 2 DIABETES MELLITUS OVERWEIGHT TYPE 2 DIABETES MELLITUS

Contacts and locations

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Locations

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Birmingham, Alabama, 35211-1320, United States
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Huntsville, Alabama, 35802, United States
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Peoria, Arizona, 85382, United States
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Phoenix, Arizona, 85020, United States

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Tempe, Arizona, 85284-3499, United States
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Tucson, Arizona, 85741, United States
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Little Rock, Arkansas, 72204, United States
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Banning, California, 92220-3082, United States
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Chula Vista, California, 91910, United States
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Covina, California, 91723-1905, United States
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Gardena, California, 90247-3583, United States
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La Mesa, California, 91942, United States
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Los Angeles, California, 91405, United States
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Sacramento, California, 95821-2640, United States
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Tarzana, California, 91356-3508, United States
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Tustin, California, 92780-7074, United States
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Washington D.C., District of Columbia, 20016, United States
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Boca Raton, Florida, 33434, United States
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Daytona Beach, Florida, 32114, United States
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Jacksonville, Florida, 32205-4785, United States
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Leesburg, Florida, 34748-5077, United States
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Melbourne, Florida, 32934-8172, United States

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South Miami, Florida, 33143, United States
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Tampa, Florida, 33613-1244, United States
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The Villages, Florida, 32162, United States

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Winter Park, Florida, 32789-4681, United States
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Canton, Georgia, 30115, United States
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Decatur, Georgia, 30030-3440, United States
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Union City, Georgia, 30291-2085, United States
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Boise, Idaho, 83704, United States
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Schaumburg, Illinois, 60173, United States
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Evansville, Indiana, 47714-7513, United States

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Indianapolis, Indiana, 46254, United States
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Valparaiso, Indiana, 46383, United States
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Kansas City, Kansas, 66112, United States
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Baton Rouge, Louisiana, 70809-3416, United States
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Metairie, Louisiana, 70006, United States
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Bowie, Maryland, 20715, United States
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Rockville, Maryland, 20854-2931, United States
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Southfield, Michigan, 48076-5412, United States
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Mankato, Minnesota, 56001, United States
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Gulfport, Mississippi, 39503-2637, United States
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Jackson, Mississippi, 39206, United States
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Olive Branch, Mississippi, 38654-3514, United States
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Columbia, Missouri, 65201, United States
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St Louis, Missouri, 63141, United States
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Las Vegas, Nevada, 89113, United States
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Jersey City, New Jersey, 07306-4004, United States
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East Northport, New York, 11731, United States
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East Syracuse, New York, 13057, United States
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New Windsor, New York, 12553-7754, United States
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Charlotte, North Carolina, 28262, United States
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Durham, North Carolina, 27701, United States
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Greenville, North Carolina, 27834-5051, United States
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Morehead City, North Carolina, 28557, United States
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Raleigh, North Carolina, 27610, United States
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Cincinnati, Ohio, 45246, United States
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Cleveland, Ohio, 44122-4330, United States
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Columbus, Ohio, 43212-3122, United States
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Dayton, Ohio, 45414, United States
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Oklahoma City, Oklahoma, 73118-2872, United States
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Eugene, Oregon, 97404-3233, United States
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Philadelphia, Pennsylvania, 19107, United States
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Pittsburgh, Pennsylvania, 15243-1800, United States
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Bluffton, South Carolina, 29910, United States
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Clemson, South Carolina, 29634, United States
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Columbia, South Carolina, 29204, United States
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Gaffney, South Carolina, 29340-4737, United States
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Memphis, Tennessee, 38119-4823, United States
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Austin, Texas, 78744-1645, United States

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Brownsville, Texas, 78520, United States
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DeSoto, Texas, 75115-2043, United States
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Frisco, Texas, 75033-4133, United States
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Houston, Texas, 77024, United States
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Mesquite, Texas, 75149, United States
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San Antonio, Texas, 78229-3272, United States

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San Antonio, Texas, 78229-3539, United States
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Sugar Land, Texas, 77478, United States
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Tomball, Texas, 77375, United States
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Waxahachie, Texas, 75165-1430, United States
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Weslaco, Texas, 78596-7288, United States
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Wichita Falls, Texas, 76301, United States
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Salt Lake City, Utah, 84124-3543, United States
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Hampton, Virginia, 23666, United States
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Seattle, Washington, 98122, United States
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Pardubice, 530 02, Czechia
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Prague, 120 00, Czechia
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Prague, 150 00, Czechia
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Uherské Hradiště, 686 01, Czechia
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Berlin, 10629, Germany
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Berlin, 10787, Germany
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Essen, 45355, Germany
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Hanover, 30159, Germany
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Athens, 106 76, Greece
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Athens, 115 27, Greece
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Athens, 115 28, Greece
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Larissa, 411 10, Greece
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Marousi, 151 23, Greece
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Palaió Fáliro, 175 62, Greece
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Pylaia, 570 01, Greece
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Thessaloniki, 546 36, Greece
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Thessaloniki, 546 42, Greece
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Biała Podlaska, 21-500, Poland
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Bydgoszcz, 85-092, Poland
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Częstochowa, 42-202, Poland
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Gdansk, 80-382, Poland
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Gdynia, 81-384, Poland
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Gdynia, 81-537, Poland
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Katowice, 40-040, Poland
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Krakow, 31-261, Poland
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Krakow, 31-501, Poland
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Lodz, 90-127, Poland
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Lodz, 91-363, Poland
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Lublin, 20-011, Poland
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Lublin, 20-362, Poland
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Poznan, 60-324, Poland
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Poznan, 60-702, Poland
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Puławy, 24-100, Poland
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Siedlce, 08-110, Poland
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Staszów, 28-200, Poland
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Torun, 87-100, Poland
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Warsaw, 00-215, Poland
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Warsaw, 00-710, Poland
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Warsaw, 01-696, Poland
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Warsaw, 02-672, Poland
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Warsaw, 03-291, Poland
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Wroclaw, 50-381, Poland
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Wroclaw, 53-673, Poland
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Cardiff, CF15 9SS, United Kingdom
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Edgbaston, B16 8QQ, United Kingdom
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Glasgow, ML43NJ, United Kingdom
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London, E1 1AG, United Kingdom
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Manchester, M11 1AA, United Kingdom
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Manchester, M156SE, United Kingdom
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Stoke-on-Trent, ST1 5SJ, United Kingdom
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Warrington, WA1 3TZ, United Kingdom

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